1sa4: Difference between revisions

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Revision as of 09:28, 25 July 2012

File:1sa4.png

Template:STRUCTURE 1sa4

human protein farnesyltransferase complexed with FPP and R115777

Template:ABSTRACT PUBMED 15170324

About this Structure

1sa4 is a 2 chain structure of Farnesyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Reid TS, Beese LS. Crystal structures of the anticancer clinical candidates R115777 (Tipifarnib) and BMS-214662 complexed with protein farnesyltransferase suggest a mechanism of FTI selectivity. Biochemistry. 2004 Jun 8;43(22):6877-84. PMID:15170324 doi:10.1021/bi049723b

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