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[[Image:3g4a.png|left|200px]]
[[Image:3g4a.png|left|200px]]


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{{STRUCTURE_3g4a|  PDB=3g4a  |  SCENE=  }}  
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===Crystal structure of flavine dependant thymidylate synthase S88A mutant from Thermotoga maritima at 1.95 angstrom resolution===
===Crystal structure of flavine dependant thymidylate synthase S88A mutant from Thermotoga maritima at 1.95 angstrom resolution===


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{{ABSTRACT_PUBMED_19370033}}
{{ABSTRACT_PUBMED_19370033}}


==About this Structure==
==About this Structure==
[[3g4a]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G4A OCA].  
[[3g4a]] is a 4 chain structure of [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G4A OCA].  
 
==See Also==
*[[Thymidylate synthase|Thymidylate synthase]]


==Reference==
==Reference==
<ref group="xtra">PMID:19370033</ref><ref group="xtra">PMID:12791256</ref><ref group="xtra">PMID:15301527</ref><references group="xtra"/>
<ref group="xtra">PMID:019370033</ref><ref group="xtra">PMID:012791256</ref><ref group="xtra">PMID:015301527</ref><references group="xtra"/>
[[Category: Thermotoga maritima msb8]]
[[Category: Thermotoga maritima msb8]]
[[Category: Kohen, A.]]
[[Category: Kohen, A.]]

Revision as of 09:39, 25 July 2012

File:3g4a.png

Template:STRUCTURE 3g4a

Crystal structure of flavine dependant thymidylate synthase S88A mutant from Thermotoga maritima at 1.95 angstrom resolution

Template:ABSTRACT PUBMED 19370033

About this Structure

3g4a is a 4 chain structure of Thymidylate synthase with sequence from Thermotoga maritima msb8. Full crystallographic information is available from OCA.

See Also

Reference

  1. Koehn EM, Fleischmann T, Conrad JA, Palfey BA, Lesley SA, Mathews II, Kohen A. An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene. Nature. 2009 Apr 16;458(7240):919-23. PMID:19370033 doi:10.1038/nature07973
  2. Mathews II, Deacon AM, Canaves JM, McMullan D, Lesley SA, Agarwalla S, Kuhn P. Functional analysis of substrate and cofactor complex structures of a thymidylate synthase-complementing protein. Structure. 2003 Jun;11(6):677-90. PMID:12791256
  3. Agrawal N, Lesley SA, Kuhn P, Kohen A. Mechanistic studies of a flavin-dependent thymidylate synthase. Biochemistry. 2004 Aug 17;43(32):10295-301. PMID:15301527 doi:10.1021/bi0490439

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