3hw1: Difference between revisions

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{{Seed}}
[[Image:3hw1.png|left|200px]]
[[Image:3hw1.png|left|200px]]


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{{STRUCTURE_3hw1|  PDB=3hw1  |  SCENE=  }}  
{{STRUCTURE_3hw1|  PDB=3hw1  |  SCENE=  }}  


===Structure of Bace (beta secretase) in complex with ligand EV2===
===Structure of Bace (beta secretase) in complex with ligand EV2===


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{{ABSTRACT_PUBMED_19799414}}
{{ABSTRACT_PUBMED_19799414}}


==About this Structure==
==About this Structure==
3HW1 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HW1 OCA].  
[[3hw1]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HW1 OCA].  
 
==See Also==
*[[Beta secretase|Beta secretase]]


==Reference==
==Reference==
<ref group="xtra">PMID:19799414</ref><references group="xtra"/>
<ref group="xtra">PMID:019799414</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
Line 32: Line 23:
[[Category: Madden, J.]]
[[Category: Madden, J.]]
[[Category: Smith, M A.]]
[[Category: Smith, M A.]]
[[Category: Alternative splicing]]
[[Category: Alzheimer's disease]]
[[Category: Alzheimer's disease]]
[[Category: Amyloid precursor protein secretase]]
[[Category: Amyloid precursor protein secretase]]
Line 46: Line 36:
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 11 20:08:23 2009''

Revision as of 10:55, 25 July 2012

File:3hw1.png

Template:STRUCTURE 3hw1

Structure of Bace (beta secretase) in complex with ligand EV2

Template:ABSTRACT PUBMED 19799414

About this Structure

3hw1 is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Godemann R, Madden J, Kramer J, Smith M, Fritz U, Hesterkamp T, Barker J, Hoppner S, Hallett D, Cesura A, Ebneth A, Kemp J. Fragment-Based Discovery of BACE1 Inhibitors Using Functional Assays. Biochemistry. 2009 Oct 23. PMID:19799414 doi:10.1021/bi901061a

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