2zhr: Difference between revisions

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{{Seed}}
[[Image:2zhr.png|left|200px]]
[[Image:2zhr.png|left|200px]]


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{{STRUCTURE_2zhr|  PDB=2zhr  |  SCENE=  }}  
{{STRUCTURE_2zhr|  PDB=2zhr  |  SCENE=  }}  


===Crystal structure of BACE1 in complex with OM99-2 at pH 5.0===
===Crystal structure of BACE1 in complex with OM99-2 at pH 5.0===


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{{ABSTRACT_PUBMED_18378702}}
{{ABSTRACT_PUBMED_18378702}}


==About this Structure==
==About this Structure==
2ZHR is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZHR OCA].  
[[2zhr]] is a 4 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZHR OCA].  
 
==See Also==
*[[Beta secretase|Beta secretase]]


==Reference==
==Reference==
<ref group="xtra">PMID:18378702</ref><references group="xtra"/>
<ref group="xtra">PMID:018378702</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
[[Category: Nukina, N.]]
[[Category: Nukina, N.]]
[[Category: Shimizu, H.]]
[[Category: Shimizu, H.]]
[[Category: Alternative splicing]]
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hydrolase/hydrolase inhibitor complex]]
[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Om99-2 complex]]
[[Category: Om99-2 complex]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:51:16 2009''

Revision as of 11:11, 25 July 2012

File:2zhr.png


Drag the structure with the mouse to rotate
2zhr, resolution 2.50Å (default scene)
Non-Standard Residues: 1OL
Gene: BACE1 (Homo sapiens)
Activity: Memapsin 2, with EC number 3.4.23.46
Related: 2zhs, 2zht, 2zhu, 2zhv
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Crystal structure of BACE1 in complex with OM99-2 at pH 5.0

Template:ABSTRACT PUBMED 18378702

About this Structure

2zhr is a 4 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Shimizu H, Tosaki A, Kaneko K, Hisano T, Sakurai T, Nukina N. Crystal structure of an active form of BACE1, an enzyme responsible for amyloid beta protein production. Mol Cell Biol. 2008 Jun;28(11):3663-71. Epub 2008 Mar 31. PMID:18378702 doi:10.1128/MCB.02185-07

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