3gbb: Difference between revisions

Revision as of 11:25, 25 July 2012

3gbb is a 2 chain structure of Ionotropic Glutamate Receptors with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Frydenvang K, Lash LL, Naur P, Postila PA, Pickering DS, Smith CM, Gajhede M, Sasaki M, Sakai R, Pentikainen OT, Swanson GT, Kastrup JS. Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine. J Biol Chem. 2009 May 22;284(21):14219-29. Epub 2009 Mar 18. PMID:19297335 doi:10.1074/jbc.M808547200
Naur P, Vestergaard B, Skov LK, Egebjerg J, Gajhede M, Kastrup JS. Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate. FEBS Lett. 2005 Feb 14;579(5):1154-60. PMID:15710405 doi:10.1016/j.febslet.2005.01.012

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 [[Image:3gbb.png|left|200px]]
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 ===X-ray strucutre of iGluR5 ligand-binding core (S1S2) in complex with MSVIII-19 at 2.10A resolution===
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