1z76: Difference between revisions

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[[Image:1z76.png|left|200px]]
[[Image:1z76.png|left|200px]]


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{{STRUCTURE_1z76|  PDB=1z76  |  SCENE=  }}  
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===Crystal structure of an acidic phospholipase A2 (BthA-I) from Bothrops jararacussu venom complexed with p-bromophenacyl bromide===
===Crystal structure of an acidic phospholipase A2 (BthA-I) from Bothrops jararacussu venom complexed with p-bromophenacyl bromide===


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{{ABSTRACT_PUBMED_16301802}}
{{ABSTRACT_PUBMED_16301802}}


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==See Also==
==See Also==
*[[Phospholipase A2]]
*[[Phospholipase A2|Phospholipase A2]]


==Reference==
==Reference==
<ref group="xtra">PMID:16301802</ref><ref group="xtra">PMID:15158738</ref><ref group="xtra">PMID:15351695</ref><references group="xtra"/>
<ref group="xtra">PMID:016301802</ref><ref group="xtra">PMID:015158738</ref><ref group="xtra">PMID:015351695</ref><references group="xtra"/>
[[Category: Bothrops jararacussu]]
[[Category: Bothrops jararacussu]]
[[Category: Fontes, M R.]]
[[Category: Fontes, M R.]]
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[[Category: Acidic phospholipase a2]]
[[Category: Acidic phospholipase a2]]
[[Category: Bothrops jararacussu venom]]
[[Category: Bothrops jararacussu venom]]
[[Category: Crystal structure]]
[[Category: Dimeric phospholipase a2]]
[[Category: Dimeric phospholipase a2]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
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[[Category: Phospholipase a2 inhibition]]
[[Category: Phospholipase a2 inhibition]]
[[Category: Platelet aggregation and hypotensive effect]]
[[Category: Platelet aggregation and hypotensive effect]]
[[Category: X-ray crystallography]]

Revision as of 11:47, 25 July 2012

File:1z76.png

Template:STRUCTURE 1z76

Crystal structure of an acidic phospholipase A2 (BthA-I) from Bothrops jararacussu venom complexed with p-bromophenacyl bromide

Template:ABSTRACT PUBMED 16301802

About this Structure

1z76 is a 2 chain structure of Phospholipase A2 with sequence from Bothrops jararacussu. Full crystallographic information is available from OCA.

See Also

Reference

  1. Magro AJ, Takeda AA, Soares AM, Fontes MR. Structure of BthA-I complexed with p-bromophenacyl bromide: possible correlations with lack of pharmacological activity. Acta Crystallogr D Biol Crystallogr. 2005 Dec;61(Pt 12):1670-7. Epub 2005, Nov 19. PMID:16301802 doi:10.1107/S0907444905029598
  2. Takeda AA, dos Santos JI, Marcussi S, Silveira LB, Soares AM, Fontes MR. Crystallization and preliminary X-ray diffraction analysis of an acidic phospholipase A(2) complexed with p-bromophenacyl bromide and alpha-tocopherol inhibitors at 1.9- and 1.45-A resolution. Biochim Biophys Acta. 2004 Jun 1;1699(1-2):281-4. PMID:15158738 doi:10.1016/j.bbapap.2004.02.005
  3. Magro AJ, Murakami MT, Marcussi S, Soares AM, Arni RK, Fontes MR. Crystal structure of an acidic platelet aggregation inhibitor and hypotensive phospholipase A2 in the monomeric and dimeric states: insights into its oligomeric state. Biochem Biophys Res Commun. 2004 Oct 8;323(1):24-31. PMID:15351695 doi:10.1016/j.bbrc.2004.08.046

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