3nox: Difference between revisions
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[[Image:3nox.png|left|200px]] | [[Image:3nox.png|left|200px]] | ||
{{STRUCTURE_3nox| PDB=3nox | SCENE= }} | {{STRUCTURE_3nox| PDB=3nox | SCENE= }} | ||
===Crystal structure of human DPP-IV in complex with Sa-(+)-(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidin-2-yl)(morpholino)methanone=== | ===Crystal structure of human DPP-IV in complex with Sa-(+)-(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidin-2-yl)(morpholino)methanone=== | ||
{{ABSTRACT_PUBMED_20684603}} | {{ABSTRACT_PUBMED_20684603}} | ||
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==See Also== | ==See Also== | ||
*[[Dipeptidyl peptidase]] | *[[Dipeptidyl peptidase|Dipeptidyl peptidase]] | ||
==Reference== | ==Reference== | ||
Revision as of 12:27, 25 July 2012
Crystal structure of human DPP-IV in complex with Sa-(+)-(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidin-2-yl)(morpholino)methanone
Template:ABSTRACT PUBMED 20684603
About this Structure
3nox is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Meng W, Brigance RP, Chao HJ, Fura A, Harrity T, Marcinkeviciene J, O'Connor SP, Tamura JK, Xie D, Zhang Y, Klei HE, Kish K, Weigelt CA, Turdi H, Wang A, Zahler R, Kirby MS, Hamann LG. Discovery of 6-(Aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidine-2- carboxamides as potent, selective dipeptidyl peptidase-4 (DPP4) inhibitors. J Med Chem. 2010 Aug 12;53(15):5620-8. PMID:20684603 doi:10.1021/jm100634a
