1s63: Difference between revisions

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{{Seed}}
[[Image:1s63.png|left|200px]]
[[Image:1s63.png|left|200px]]


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{{STRUCTURE_1s63|  PDB=1s63  |  SCENE=  }}  
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===Human protein farnesyltransferase complexed with L-778,123 and FPP===
===Human protein farnesyltransferase complexed with L-778,123 and FPP===


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{{ABSTRACT_PUBMED_15248757}}
{{ABSTRACT_PUBMED_15248757}}


==About this Structure==
==About this Structure==
1S63 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S63 OCA].  
[[1s63]] is a 2 chain structure of [[Farnesyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S63 OCA].  
 
==See Also==
*[[Farnesyltransferase|Farnesyltransferase]]


==Reference==
==Reference==
<ref group="xtra">PMID:15248757</ref><references group="xtra"/>
<ref group="xtra">PMID:015248757</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein farnesyltransferase]]
[[Category: Protein farnesyltransferase]]
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[[Category: Protein prenylation]]
[[Category: Protein prenylation]]
[[Category: Ra]]
[[Category: Ra]]
 
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:17:54 2009''

Revision as of 13:06, 25 July 2012

File:1s63.png

Template:STRUCTURE 1s63

Human protein farnesyltransferase complexed with L-778,123 and FPP

Template:ABSTRACT PUBMED 15248757

About this Structure

1s63 is a 2 chain structure of Farnesyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Reid TS, Long SB, Beese LS. Crystallographic analysis reveals that anticancer clinical candidate L-778,123 inhibits protein farnesyltransferase and geranylgeranyltransferase-I by different binding modes. Biochemistry. 2004 Jul 20;43(28):9000-8. PMID:15248757 doi:10.1021/bi049280b

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