3pa3: Difference between revisions

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{{Seed}}
[[Image:3pa3.png|left|200px]]
[[Image:3pa3.jpg|left|200px]]


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{{STRUCTURE_3pa3|  PDB=3pa3  |  SCENE=  }}  
{{STRUCTURE_3pa3|  PDB=3pa3  |  SCENE=  }}  


===X-ray crystal structure of compound 70 bound to human CHK1 kinase domain===
===X-ray crystal structure of compound 70 bound to human CHK1 kinase domain===


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{{ABSTRACT_PUBMED_21074424}}
{{ABSTRACT_PUBMED_21074424}}


==About this Structure==
==About this Structure==
3PA3 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA3 OCA].  
[[3pa3]] is a 1 chain structure of [[Serine/threonine protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA3 OCA].  
 
==See Also==
*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:21074424</ref><references group="xtra"/>
<ref group="xtra">PMID:021074424</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transferase-transferase inhibitor complex]]
[[Category: Transferase-transferase inhibitor complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec  8 11:54:09 2010''

Revision as of 13:17, 25 July 2012

File:3pa3.png

Template:STRUCTURE 3pa3

X-ray crystal structure of compound 70 bound to human CHK1 kinase domain

Template:ABSTRACT PUBMED 21074424

About this Structure

3pa3 is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Zhao L, Zhang Y, Dai C, Guzi T, Wiswell D, Seghezzi W, Parry D, Fischmann T, Siddiqui MA. Design, synthesis and SAR of thienopyridines as potent CHK1 inhibitors. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7216-21. Epub 2010 Oct 26. PMID:21074424 doi:10.1016/j.bmcl.2010.10.105

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