1pk0: Difference between revisions

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[[Image:1pk0.png|left|200px]]
[[Image:1pk0.png|left|200px]]


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{{STRUCTURE_1pk0|  PDB=1pk0  |  SCENE=  }}  
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===Crystal Structure of the EF3-CaM complexed with PMEApp===
===Crystal Structure of the EF3-CaM complexed with PMEApp===


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{{ABSTRACT_PUBMED_14978283}}
{{ABSTRACT_PUBMED_14978283}}


==About this Structure==
==About this Structure==
[[1pk0]] is a 6 chain structure of [[Adenylyl cyclase]] and [[Calmodulin]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PK0 OCA].  
[[1pk0]] is a 6 chain structure of [[Adenylyl cyclase]], [[Anthrax edema factor]] and [[Calmodulin]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PK0 OCA].  


==See Also==
==See Also==
*[[Adenylyl cyclase]]
*[[Adenylyl cyclase|Adenylyl cyclase]]
*[[Calmodulin]]
*[[Anthrax edema factor|Anthrax edema factor]]
*[[Calmodulin|Calmodulin]]


==Reference==
==Reference==
<ref group="xtra">PMID:14978283</ref><ref group="xtra">PMID:12485993</ref><references group="xtra"/>
<ref group="xtra">PMID:014978283</ref><ref group="xtra">PMID:012485993</ref><references group="xtra"/>
[[Category: Adenylate cyclase]]
[[Category: Adenylate cyclase]]
[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
Line 34: Line 24:
[[Category: Cam]]
[[Category: Cam]]
[[Category: Edema factor]]
[[Category: Edema factor]]
[[Category: Lyase/metal binding protein complex]]
[[Category: Lyase-metal binding protein complex]]
[[Category: Prodrug complex]]
[[Category: Prodrug complex]]

Revision as of 13:56, 25 July 2012

File:1pk0.png

Template:STRUCTURE 1pk0

Crystal Structure of the EF3-CaM complexed with PMEApp

Template:ABSTRACT PUBMED 14978283

About this Structure

1pk0 is a 6 chain structure of Adenylyl cyclase, Anthrax edema factor and Calmodulin with sequence from Bacillus anthracis and Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Shen Y, Zhukovskaya NL, Zimmer MI, Soelaiman S, Bergson P, Wang CR, Gibbs CS, Tang WJ. Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):3242-7. Epub 2004 Feb 20. PMID:14978283 doi:10.1073/pnas.0306552101
  2. Shen Y, Lee YS, Soelaiman S, Bergson P, Lu D, Chen A, Beckingham K, Grabarek Z, Mrksich M, Tang WJ. Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins. EMBO J. 2002 Dec 16;21(24):6721-32. PMID:12485993

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