1ai8: Difference between revisions

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[[Image:1ai8.png|left|200px]]
[[Image:1ai8.png|left|200px]]


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{{STRUCTURE_1ai8|  PDB=1ai8  |  SCENE=  }}  
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===HUMAN ALPHA-THROMBIN TERNARY COMPLEX WITH THE EXOSITE INHIBITOR HIRUGEN AND ACTIVE SITE INHIBITOR PHCH2OCO-D-DPA-PRO-BOROMPG===
===HUMAN ALPHA-THROMBIN TERNARY COMPLEX WITH THE EXOSITE INHIBITOR HIRUGEN AND ACTIVE SITE INHIBITOR PHCH2OCO-D-DPA-PRO-BOROMPG===


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{{ABSTRACT_PUBMED_1304349}}
{{ABSTRACT_PUBMED_1304349}}


==About this Structure==
==About this Structure==
[[1ai8]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AI8 OCA].  
[[1ai8]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AI8 OCA].  


==See Also==
==See Also==
*[[Hirudin]]
*[[Hirudin|Hirudin]]
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:1304349</ref><references group="xtra"/>
<ref group="xtra">PMID:001304349</ref><references group="xtra"/>
[[Category: Hirudo medicinalis]]
[[Category: Hirudo medicinalis]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 39: Line 29:
[[Category: Skordalakes, E.]]
[[Category: Skordalakes, E.]]
[[Category: Tyrrel, R.]]
[[Category: Tyrrel, R.]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation-hydrolase inhibitor complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Serine proteinase]]

Revision as of 14:45, 25 July 2012

File:1ai8.png

Template:STRUCTURE 1ai8

HUMAN ALPHA-THROMBIN TERNARY COMPLEX WITH THE EXOSITE INHIBITOR HIRUGEN AND ACTIVE SITE INHIBITOR PHCH2OCO-D-DPA-PRO-BOROMPG

Template:ABSTRACT PUBMED 1304349

About this Structure

1ai8 is a 3 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Bode W, Turk D, Karshikov A. The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships. Protein Sci. 1992 Apr;1(4):426-71. PMID:1304349

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