2hh5: Difference between revisions

Revision as of 16:28, 25 July 2012

2hh5 is a 2 chain structure of Cathepsin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Tully DC, Liu H, Chatterjee AK, Alper PB, Epple R, Williams JA, Roberts MJ, Woodmansee DH, Masick BT, Tumanut C, Li J, Spraggon G, Hornsby M, Chang J, Tuntland T, Hollenbeck T, Gordon P, Harris JL, Karanewsky DS. Synthesis and SAR of arylaminoethyl amides as noncovalent inhibitors of cathepsin S: P3 cyclic ethers. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5112-7. Epub 2006 Jul 28. PMID:16876402 doi:https://dx.doi.org/10.1016/j.bmcl.2006.07.033
Tully DC, Liu H, Alper PB, Chatterjee AK, Epple R, Roberts MJ, Williams JA, Nguyen KT, Woodmansee DH, Tumanut C, Li J, Spraggon G, Chang J, Tuntland T, Harris JL, Karanewsky DS. Synthesis and evaluation of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 3: heterocyclic P3. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1975-80. Epub 2006 Jan 30. PMID:16446091 doi:https://dx.doi.org/10.1016/j.bmcl.2005.12.095

@@ Line 1: / Line 1: @@
 [[Image:2hh5.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_2hh5", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_2hh5|  PDB=2hh5  |  SCENE=  }}
 ===Crystal Structure of Cathepsin S in complex with a Zinc mediated non-covalent arylaminoethyl amide===
-<!--
-The line below this paragraph, {{ABSTRACT_PUBMED_16876402}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 16876402 is the PubMed ID number.
--->
 {{ABSTRACT_PUBMED_16876402}}
@@ Line 22: / Line 11: @@
 ==See Also==
-*[[Cathepsin]]
+*[[Cathepsin|Cathepsin]]
 ==Reference==
-<ref group="xtra">PMID:16876402</ref><ref group="xtra">PMID:16446091</ref><references group="xtra"/>
+<ref group="xtra">PMID:016876402</ref><ref group="xtra">PMID:016446091</ref><references group="xtra"/>
 [[Category: Cathepsin S]]
 [[Category: Homo sapiens]]
@@ Line 39: / Line 28: @@
 [[Category: Inhibition]]
 [[Category: Noncovalent]]
-[[Category: Zinc]]