2wez: Difference between revisions
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Revision as of 16:38, 25 July 2012
HUMAN BACE-1 IN COMPLEX WITH 1-ETHYL-N-((1S,2R)-2-HYDROXY-3-(((3-(METHYLOXY)PHENYL)METHYL)AMINO)-1-(PHENYLMETHYL) PROPYL)-4-(2-OXO-1-PYRROLIDINYL)-1H-INDOLE-6-CARBOXAMIDE
Template:ABSTRACT PUBMED 19428244
About this Structure
2wez is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Charrier N, Clarke B, Cutler L, Demont E, Dingwall C, Dunsdon R, Hawkins J, Howes C, Hubbard J, Hussain I, Maile G, Matico R, Mosley J, Naylor A, O'Brien A, Redshaw S, Rowland P, Soleil V, Smith KJ, Sweitzer S, Theobald P, Vesey D, Walter DS, Wayne G. Second generation of BACE-1 inhibitors. Part 1: The need for improved pharmacokinetics. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3664-8. Epub 2009 Apr 17. PMID:19428244 doi:10.1016/j.bmcl.2009.03.165
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Categories:
- Pages with broken file links
- Homo sapiens
- Memapsin 2
- Brien, A O.
- Charrier, N.
- Clarke, B.
- Cutler, L.
- Demont, E.
- Dingwall, C.
- Dunsdon, R.
- Hawkins, J.
- Howes, C.
- Hubbard, J.
- Hussain, I.
- Maile, G.
- Matico, R.
- Mosley, J.
- Naylor, A.
- Redshaw, S.
- Rowland, P.
- Smith, K J.
- Soleil, V.
- Sweitzer, S.
- Theobald, P.
- Vesey, D.
- Walter, D S.
- Wayne, G.
- Asp-2
- Aspartyl protease
- Bace-1
- Beta-secretase
- Beta-site app cleaving enzyme
- Disulfide bond
- Glycoprotein
- Hydrolase
- Memapsin-2
- Membrane
- Protease
- Transmembrane
- Zymogen