3dm6: Difference between revisions

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{{Seed}}
[[Image:3dm6.png|left|200px]]
[[Image:3dm6.jpg|left|200px]]


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{{STRUCTURE_3dm6|  PDB=3dm6  |  SCENE=  }}  
{{STRUCTURE_3dm6|  PDB=3dm6  |  SCENE=  }}  


===Beta-secretase 1 complexed with statine-based inhibitor===
===Beta-secretase 1 complexed with statine-based inhibitor===


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{{ABSTRACT_PUBMED_18842420}}
{{ABSTRACT_PUBMED_18842420}}


==About this Structure==
==About this Structure==
3DM6 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DM6 OCA].  
[[3dm6]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DM6 OCA].  
 
==See Also==
*[[Beta secretase|Beta secretase]]


==Reference==
==Reference==
Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues., Back M, Nyhlen J, Kvarnstrom I, Appelgren S, Borkakoti N, Jansson K, Lindberg J, Nystrom S, Hallberg A, Rosenquist S, Samuelsson B, Bioorg Med Chem. 2008 Nov 1;16(21):9471-86. Epub 2008 Sep 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18842420 18842420]
<ref group="xtra">PMID:018842420</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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[[Category: Lindberg, J.]]
[[Category: Lindberg, J.]]
[[Category: Nystrom, S.]]
[[Category: Nystrom, S.]]
[[Category: Alternative splicing]]
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: Bace]]
[[Category: Bace]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 17 13:43:10 2008''

Revision as of 17:10, 25 July 2012

File:3dm6.png

Template:STRUCTURE 3dm6

Beta-secretase 1 complexed with statine-based inhibitor

Template:ABSTRACT PUBMED 18842420

About this Structure

3dm6 is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Back M, Nyhlen J, Kvarnstrom I, Appelgren S, Borkakoti N, Jansson K, Lindberg J, Nystrom S, Hallberg A, Rosenquist S, Samuelsson B. Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues. Bioorg Med Chem. 2008 Nov 1;16(21):9471-86. Epub 2008 Sep 19. PMID:18842420 doi:S0968-0896(08)00877-8

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