3dm6: Difference between revisions

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Revision as of 17:10, 25 July 2012

File:3dm6.png

Template:STRUCTURE 3dm6

Beta-secretase 1 complexed with statine-based inhibitor

Template:ABSTRACT PUBMED 18842420

About this Structure

3dm6 is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Back M, Nyhlen J, Kvarnstrom I, Appelgren S, Borkakoti N, Jansson K, Lindberg J, Nystrom S, Hallberg A, Rosenquist S, Samuelsson B. Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues. Bioorg Med Chem. 2008 Nov 1;16(21):9471-86. Epub 2008 Sep 19. PMID:18842420 doi:S0968-0896(08)00877-8

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