2vh0: Difference between revisions
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[[Image:2vh0.png|left|200px]] | [[Image:2vh0.png|left|200px]] | ||
{{STRUCTURE_2vh0| PDB=2vh0 | SCENE= }} | {{STRUCTURE_2vh0| PDB=2vh0 | SCENE= }} | ||
===STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: BIARYL PYRROLIDIN-2-ONES INCORPORATING BASIC HETEROCYCLIC MOTIFS=== | ===STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: BIARYL PYRROLIDIN-2-ONES INCORPORATING BASIC HETEROCYCLIC MOTIFS=== | ||
{{ABSTRACT_PUBMED_18053714}} | {{ABSTRACT_PUBMED_18053714}} | ||
==About this Structure== | ==About this Structure== | ||
[[2vh0]] is a 2 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VH0 OCA]. | |||
==See Also== | |||
*[[Factor Xa|Factor Xa]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:018053714</ref><references group="xtra"/> | |||
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Zhou, P.]] | [[Category: Zhou, P.]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Complex]] | [[Category: Complex]] | ||
| Line 60: | Line 50: | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Hydroxylation]] | [[Category: Hydroxylation]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 17:16, 25 July 2012
STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: BIARYL PYRROLIDIN-2-ONES INCORPORATING BASIC HETEROCYCLIC MOTIFS
Template:ABSTRACT PUBMED 18053714
About this Structure
2vh0 is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Young RJ, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chan C, Charbaut M, Convery MA, Diallo H, Hortense E, Irving WR, Kelly HA, King NP, Kleanthous S, Mason AM, Pateman AJ, Patikis AN, Pinto IL, Pollard DR, Senger S, Shah GP, Toomey JR, Watson NS, Weston HE, Zhou P. Structure and property based design of factor Xa inhibitors: biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs. Bioorg Med Chem Lett. 2008 Jan 1;18(1):28-33. Epub 2007 Nov 13. PMID:18053714 doi:S0960-894X(07)01328-5
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Coagulation factor Xa
- Homo sapiens
- Borthwick, A D.
- Brown, D.
- Burns-Kurtis, C L.
- Campbell, M.
- Chan, C.
- Charbaut, M.
- Convery, M A.
- Diallo, H.
- Hortense, E.
- Irving, W R.
- Kelly, H A.
- King, N P.
- Kleanthous, S.
- Mason, A M.
- Pateman, A J.
- Patikis, A.
- Pinto, I L.
- Pollard, D R.
- Senger, S.
- Shah, G P.
- Toomey, J R.
- Watson, N S.
- Weston, H E.
- Young, R J.
- Zhou, P.
- Blood coagulation
- Cleavage on pair of basic residue
- Complex
- Egf-like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Hydroxylation
- Protease
- Serine protease
- Zymogen
