2w7x: Difference between revisions
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[[Image:2w7x.png|left|200px]] | [[Image:2w7x.png|left|200px]] | ||
{{STRUCTURE_2w7x| PDB=2w7x | SCENE= }} | {{STRUCTURE_2w7x| PDB=2w7x | SCENE= }} | ||
===CELLULAR INHIBITION OF CHECKPOINT KINASE 2 AND POTENTIATION OF CYTOTOXIC DRUGS BY NOVEL CHK2 INHIBITOR PV1019=== | ===CELLULAR INHIBITION OF CHECKPOINT KINASE 2 AND POTENTIATION OF CYTOTOXIC DRUGS BY NOVEL CHK2 INHIBITOR PV1019=== | ||
{{ABSTRACT_PUBMED_19741151}} | {{ABSTRACT_PUBMED_19741151}} | ||
==About this Structure== | ==About this Structure== | ||
[[2w7x]] is a 1 chain structure of [[Serine/threonine protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7X OCA]. | |||
==See Also== | |||
*[[Serine/threonine protein kinase|Serine/threonine protein kinase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019741151</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Waugh, D S.]] | [[Category: Waugh, D S.]] | ||
[[Category: Zhang, G.]] | [[Category: Zhang, G.]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
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[[Category: Nucleus]] | [[Category: Nucleus]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Potentiation]] | [[Category: Potentiation]] | ||
[[Category: Proto-oncogene]] | [[Category: Proto-oncogene]] | ||
[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 18:03, 25 July 2012
CELLULAR INHIBITION OF CHECKPOINT KINASE 2 AND POTENTIATION OF CYTOTOXIC DRUGS BY NOVEL CHK2 INHIBITOR PV1019
Template:ABSTRACT PUBMED 19741151
About this Structure
2w7x is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Jobson AG, Lountos GT, Lorenzi PL, Llamas J, Connelly J, Cerna D, Tropea JE, Onda A, Zoppoli G, Kondapaka S, Zhang G, Caplen NJ, Cardellina JH 2nd, Yoo SS, Monks A, Self C, Waugh DS, Shoemaker RH, Pommier Y. Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide]. J Pharmacol Exp Ther. 2009 Dec;331(3):816-26. Epub 2009 Sep 9. PMID:19741151 doi:10.1124/jpet.109.154997
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Caplen, N J.
- Caredellina, J H.
- Connelly, J.
- Jobson, A G.
- Kondapaka, S.
- Llamas, J.
- Lorenzi, P L.
- Lountos, G T.
- Monks, A.
- Onda, A.
- Pommier, Y.
- Self, C.
- Shoemaker, R H.
- Tropea, J E.
- Waugh, D S.
- Zhang, G.
- Atp-binding
- Cell cycle
- Chk2 inhibitor
- Co-crystal structure
- Disease mutation
- Kinase
- Li-fraumeni syndrome
- Magnesium
- Metal-binding
- Nucleotide-binding
- Nucleus
- Phosphoprotein
- Potentiation
- Proto-oncogene
- Serine/threonine-protein kinase
- Transferase
