3kcg: Difference between revisions

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{{Seed}}
[[Image:3kcg.png|left|200px]]
[[Image:3kcg.jpg|left|200px]]


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{{STRUCTURE_3kcg|  PDB=3kcg  |  SCENE=  }}  
{{STRUCTURE_3kcg|  PDB=3kcg  |  SCENE=  }}  


===Crystal structure of the antithrombin-factor IXa-pentasaccharide complex===
===Crystal structure of the antithrombin-factor IXa-pentasaccharide complex===


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{{ABSTRACT_PUBMED_20080729}}
{{ABSTRACT_PUBMED_20080729}}


==Disease==
==About this Structure==
Known disease associated with this structure: Hemophilia B OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300746 300746]]
[[3kcg]] is a 3 chain structure of [[Antithrombin]] and [[Factor IX]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KCG OCA].


==About this Structure==
==See Also==
3KCG is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KCG OCA].
*[[Antithrombin|Antithrombin]]
*[[Factor IX|Factor IX]]


==Reference==
==Reference==
<ref group="xtra">PMID:20080729</ref><references group="xtra"/>
<ref group="xtra">PMID:020080729</ref><references group="xtra"/>
[[Category: Coagulation factor IXa]]
[[Category: Coagulation factor IXa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Johnson, D J.D.]]
[[Category: Johnson, D J.D.]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
[[Category: Calcium]]
[[Category: Disulfide bond]]
[[Category: Disulfide bond]]
[[Category: Egf-like domain]]
[[Category: Egf-like domain]]
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[[Category: Heparin-binding]]
[[Category: Heparin-binding]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Hydrolase inhibitor]]
[[Category: Michaelis complex]]
[[Category: Michaelis complex]]
[[Category: Pharmaceutical]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Protease inhibitor]]
[[Category: Protease inhibitor]]
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[[Category: Thrombophilia]]
[[Category: Thrombophilia]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb  3 09:34:14 2010''

Revision as of 18:05, 25 July 2012

File:3kcg.png

Template:STRUCTURE 3kcg

Crystal structure of the antithrombin-factor IXa-pentasaccharide complex

Template:ABSTRACT PUBMED 20080729

About this Structure

3kcg is a 3 chain structure of Antithrombin and Factor IX with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Johnson DJ, Langdown J, Huntington JA. Molecular basis of factor IXa recognition by heparin-activated antithrombin revealed by a 1.7-A structure of the ternary complex. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):645-50. Epub 2009 Dec 22. PMID:20080729

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