3k9x: Difference between revisions

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{{Seed}}
[[Image:3k9x.png|left|200px]]
[[Image:3k9x.jpg|left|200px]]


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===X-ray crystal structure of human fxa in complex with (S)-N-((2-METHYLBENZOFURAN-5-YLAMINO)(2-OXO-1-(2-OXO-2- (PYRROLIDIN-1-YL)ETHYL)AZEPAN-3- YLAMINO)METHYLENE)NICOTINAMIDE===
===X-ray crystal structure of human fxa in complex with (S)-N-((2-METHYLBENZOFURAN-5-YLAMINO)(2-OXO-1-(2-OXO-2- (PYRROLIDIN-1-YL)ETHYL)AZEPAN-3- YLAMINO)METHYLENE)NICOTINAMIDE===


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{{ABSTRACT_PUBMED_19896847}}
{{ABSTRACT_PUBMED_19896847}}


==About this Structure==
==About this Structure==
3K9X is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K9X OCA].  
[[3k9x]] is a 4 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K9X OCA].  
 
==See Also==
*[[Factor Xa|Factor Xa]]


==Reference==
==Reference==
<ref group="xtra">PMID:19896847</ref><references group="xtra"/>
<ref group="xtra">PMID:019896847</ref><references group="xtra"/>
[[Category: Coagulation factor Xa]]
[[Category: Coagulation factor Xa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 33: Line 24:
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation factor]]
[[Category: Blood coagulation factor]]
[[Category: Calcium]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Disulfide bond]]
[[Category: Disulfide bond]]
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Hydroxylation]]
[[Category: Hydroxylation]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 16 13:09:13 2009''

Revision as of 18:06, 25 July 2012

File:3k9x.png

Template:STRUCTURE 3k9x

X-ray crystal structure of human fxa in complex with (S)-N-((2-METHYLBENZOFURAN-5-YLAMINO)(2-OXO-1-(2-OXO-2- (PYRROLIDIN-1-YL)ETHYL)AZEPAN-3- YLAMINO)METHYLENE)NICOTINAMIDE

Template:ABSTRACT PUBMED 19896847

About this Structure

3k9x is a 4 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Shi Y, Li C, O'Connor SP, Zhang J, Shi M, Bisaha SN, Wang Y, Sitkoff D, Pudzianowski AT, Huang C, Klei HE, Kish K, Yanchunas J Jr, Liu EC, Hartl KS, Seiler SM, Steinbacher TE, Schumacher WA, Atwal KS, Stein PD. Aroylguanidine-based factor Xa inhibitors: the discovery of BMS-344577. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6882-9. Epub 2009 Oct 23. PMID:19896847 doi:10.1016/j.bmcl.2009.10.084

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