3ee0: Difference between revisions
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[[Image:3ee0.png|left|200px]] | |||
[[Image:3ee0. | |||
{{STRUCTURE_3ee0| PDB=3ee0 | SCENE= }} | {{STRUCTURE_3ee0| PDB=3ee0 | SCENE= }} | ||
===Crystal Structure of the W215A/E217A Mutant of Human Thrombin (space group P2(1)2(1)2(1))=== | ===Crystal Structure of the W215A/E217A Mutant of Human Thrombin (space group P2(1)2(1)2(1))=== | ||
{{ABSTRACT_PUBMED_15252033}} | |||
== | ==About this Structure== | ||
[[3ee0]] is a 2 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EE0 OCA]. | |||
== | ==See Also== | ||
*[[Thrombin|Thrombin]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:015252033</ref><ref group="xtra">PMID:019586901</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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[[Category: Acute phase]] | [[Category: Acute phase]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Kringle]] | [[Category: Kringle]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 18:13, 25 July 2012
Crystal Structure of the W215A/E217A Mutant of Human Thrombin (space group P2(1)2(1)2(1))
Template:ABSTRACT PUBMED 15252033
About this Structure
3ee0 is a 2 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Pineda AO, Chen ZW, Caccia S, Cantwell AM, Savvides SN, Waksman G, Mathews FS, Di Cera E. The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket. J Biol Chem. 2004 Sep 17;279(38):39824-8. Epub 2004 Jul 13. PMID:15252033 doi:https://dx.doi.org/10.1074/jbc.M407272200
- Gandhi PS, Page MJ, Chen Z, Bush-Pelc L, Di Cera E. Mechanism of the anticoagulant activity of thrombin mutant W215A/E217A. J Biol Chem. 2009 Sep 4;284(36):24098-105. Epub 2009 Jul 8. PMID:19586901 doi:10.1074/jbc.M109.025403
