3bsa: Difference between revisions

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{{Seed}}
[[Image:3bsa.png|left|200px]]
[[Image:3bsa.jpg|left|200px]]


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{{STRUCTURE_3bsa|  PDB=3bsa  |  SCENE=  }}  
{{STRUCTURE_3bsa|  PDB=3bsa  |  SCENE=  }}  


===Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor===
===Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor===


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{{ABSTRACT_PUBMED_18242088}}
{{ABSTRACT_PUBMED_18242088}}


==About this Structure==
==About this Structure==
3BSA is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BSA OCA].  
[[3bsa]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BSA OCA].  
 
==See Also==
*[[RNA polymerase|RNA polymerase]]


==Reference==
==Reference==
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5- hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine., Zhou Y, Webber SE, Murphy DE, Li LS, Dragovich PS, Tran CV, Sun Z, Ruebsam F, Shah AM, Tsan M, Showalter RE, Patel R, Li B, Zhao Q, Han Q, Hermann T, Kissinger CR, Lebrun L, Sergeeva MV, Kirkovsky L, Bioorg Med Chem Lett. 2008 Feb 15;18(4):1413-8. Epub 2008 Jan 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18242088 18242088]
<ref group="xtra">PMID:018242088</ref><references group="xtra"/>
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
[[Category: Viruses]]
[[Category: Viruses]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Viral nucleoprotein]]
[[Category: Viral nucleoprotein]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 24 11:29:14 2008''

Revision as of 18:33, 25 July 2012

File:3bsa.png

Template:STRUCTURE 3bsa

Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor

Template:ABSTRACT PUBMED 18242088

About this Structure

3bsa is a 2 chain structure of RNA polymerase with sequence from Viruses. Full crystallographic information is available from OCA.

See Also

Reference

  1. Zhou Y, Webber SE, Murphy DE, Li LS, Dragovich PS, Tran CV, Sun Z, Ruebsam F, Shah AM, Tsan M, Showalter RE, Patel R, Li B, Zhao Q, Han Q, Hermann T, Kissinger CR, Lebrun L, Sergeeva MV, Kirkovsky L. Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5- hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1413-8. Epub 2008 Jan 8. PMID:18242088 doi:S0960-894X(08)00010-3

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