2vw5: Difference between revisions

Revision as of 18:42, 25 July 2012

2vw5 is a 4 chain structure of Heat Shock Proteins with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Zhang MQ, Gaisser S, Nur-E-Alam M, Sheehan LS, Vousden WA, Gaitatzis N, Peck G, Coates NJ, Moss SJ, Radzom M, Foster TA, Sheridan RM, Gregory MA, Roe SM, Prodromou C, Pearl L, Boyd SM, Wilkinson B, Martin CJ. Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitors. J Med Chem. 2008 Sep 25;51(18):5494-7. PMID:18800759 doi:10.1021/jm8006068

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 [[Image:2vw5.png|left|200px]]
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 {{STRUCTURE_2vw5|  PDB=2vw5  |  SCENE=  }}
 ===STRUCTURE OF THE HSP90 INHIBITOR 7-O-CARBAMOYLPREMACBECIN BOUND TO THE N- TERMINUS OF YEAST HSP90===
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 ==See Also==
-*[[Heat Shock Proteins]]
+*[[Heat Shock Proteins|Heat Shock Proteins]]
 ==Reference==
-<ref group="xtra">PMID:18800759</ref><references group="xtra"/>
+<ref group="xtra">PMID:018800759</ref><references group="xtra"/>
 [[Category: Saccharomyces cerevisiae]]
 [[Category: Pearl, L H.]]
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 [[Category: Atpase]]
 [[Category: Chaperone]]
-[[Category: Cytoplasm]]
 [[Category: Inhibitor]]
 [[Category: Nucleotide-binding]]
 [[Category: Stress response]]