3i7i: Difference between revisions

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Revision as of 18:53, 25 July 2012

File:3i7i.png

Template:STRUCTURE 3i7i

MMP-13 in complex with a non zinc-chelating inhibitor

Template:ABSTRACT PUBMED 19692239

About this Structure

3i7i is a 2 chain structure of Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Heim-Riether A, Taylor SJ, Liang S, Gao DA, Xiong Z, Michael August E, Collins BK, Farmer BT 2nd, Haverty K, Hill-Drzewi M, Junker HD, Mariana Margarit S, Moss N, Neumann T, Proudfoot JR, Keenan LS, Sekul R, Zhang Q, Li J, Farrow NA. Improving potency and selectivity of a new class of non-Zn-chelating MMP-13 inhibitors. Bioorg Med Chem Lett. 2009 Sep 15;19(18):5321-4. Epub 2009 Aug 3. PMID:19692239 doi:10.1016/j.bmcl.2009.07.151

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