2gpl: Difference between revisions

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[[Image:2gpl.png|left|200px]]
[[Image:2gpl.png|left|200px]]


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{{STRUCTURE_2gpl|  PDB=2gpl  |  SCENE=  }}  
{{STRUCTURE_2gpl|  PDB=2gpl  |  SCENE=  }}  


===TMC-95 based biphenyl-ether macrocycles: specific proteasome inhibitors===
===TMC-95 based biphenyl-ether macrocycles: specific proteasome inhibitors===


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{{ABSTRACT_PUBMED_16793518}}
{{ABSTRACT_PUBMED_16793518}}


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==See Also==
==See Also==
*[[Proteasome]]
*[[Proteasome|Proteasome]]


==Reference==
==Reference==
<ref group="xtra">PMID:16793518</ref><references group="xtra"/>
<ref group="xtra">PMID:016793518</ref><references group="xtra"/>
[[Category: Proteasome endopeptidase complex]]
[[Category: Proteasome endopeptidase complex]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Moroder, M.]]
[[Category: Moroder, M.]]
[[Category: Weyher, E.]]
[[Category: Weyher, E.]]
[[Category: Hydrolase]]
[[Category: Ntn-hydrolase]]
[[Category: Ntn-hydrolase]]
[[Category: Proteasomal subunit fold represents an antiparallel beta-sheet flanked by helice]]
[[Category: Proteasomal subunit fold represents an antiparallel beta-sheet flanked by helice]]

Revision as of 19:03, 25 July 2012

File:2gpl.png

Template:STRUCTURE 2gpl

TMC-95 based biphenyl-ether macrocycles: specific proteasome inhibitors

Template:ABSTRACT PUBMED 16793518

About this Structure

2gpl is a 28 chain structure of Proteasome with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

See Also

Reference

  1. Groll M, Gotz M, Kaiser M, Weyher E, Moroder L. TMC-95-based inhibitor design provides evidence for the catalytic versatility of the proteasome. Chem Biol. 2006 Jun;13(6):607-14. PMID:16793518 doi:10.1016/j.chembiol.2006.04.005

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