2fbr: Difference between revisions

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{{Seed}}
[[Image:2fbr.png|left|200px]]
[[Image:2fbr.png|left|200px]]


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{{STRUCTURE_2fbr|  PDB=2fbr  |  SCENE=  }}  
{{STRUCTURE_2fbr|  PDB=2fbr  |  SCENE=  }}  


===Human transthyretin (TTR) complexed with bivalant amyloid inhibitor (4 carbon linker)===
===Human transthyretin (TTR) complexed with bivalant amyloid inhibitor (4 carbon linker)===


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{{ABSTRACT_PUBMED_14583036}}
{{ABSTRACT_PUBMED_14583036}}


==About this Structure==
==About this Structure==
2FBR is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBR OCA].  
[[2fbr]] is a 2 chain structure of [[Transthyretin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBR OCA].  
 
==See Also==
*[[Transthyretin|Transthyretin]]


==Reference==
==Reference==
<ref group="xtra">PMID:14583036</ref><references group="xtra"/>
<ref group="xtra">PMID:014583036</ref><ref group="xtra">PMID:020081815</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Kelly, J W.]]
[[Category: Kelly, J W.]]
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[[Category: Sacchettini, J C.]]
[[Category: Sacchettini, J C.]]
[[Category: Amyloid]]
[[Category: Amyloid]]
[[Category: Hormone/growth factor complex]]
[[Category: Hormone-growth factor complex]]
[[Category: Transthyretin]]
[[Category: Transthyretin]]
[[Category: Ttr]]
[[Category: Ttr]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 20 12:01:34 2010''

Revision as of 19:24, 25 July 2012

File:2fbr.png

Template:STRUCTURE 2fbr

Human transthyretin (TTR) complexed with bivalant amyloid inhibitor (4 carbon linker)

Template:ABSTRACT PUBMED 14583036

About this Structure

2fbr is a 2 chain structure of Transthyretin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Green NS, Palaninathan SK, Sacchettini JC, Kelly JW. Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization. J Am Chem Soc. 2003 Nov 5;125(44):13404-14. PMID:14583036 doi:10.1021/ja030294z
  2. Choi S, Connelly S, Reixach N, Wilson IA, Kelly JW. Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma. Nat Chem Biol. 2010 Feb;6(2):133-9. PMID:20081815 doi:10.1038/nchembio.281

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