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[[Image:3kjs.png|left|200px]]
[[Image:3kjs.png|left|200px]]


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{{STRUCTURE_3kjs|  PDB=3kjs  |  SCENE=  }}  
{{STRUCTURE_3kjs|  PDB=3kjs  |  SCENE=  }}  


===Crystal Structure of T. cruzi DHFR-TS with 3 high affinity DHFR inhibitors: DQ1 inhibitor complex===
===Crystal Structure of T. cruzi DHFR-TS with 3 high affinity DHFR inhibitors: DQ1 inhibitor complex===


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The line below this paragraph, {{ABSTRACT_PUBMED_20452776}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_20452776}}
{{ABSTRACT_PUBMED_20452776}}


==About this Structure==
==About this Structure==
[[3kjs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KJS OCA].  
[[3kjs]] is a 4 chain structure of [[Dihydrofolate reductase]] and [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KJS OCA].  
 
==See Also==
*[[Dihydrofolate reductase|Dihydrofolate reductase]]
*[[Thymidylate synthase|Thymidylate synthase]]


==Reference==
==Reference==
<ref group="xtra">PMID:20452776</ref><references group="xtra"/>
<ref group="xtra">PMID:020452776</ref><references group="xtra"/>
[[Category: Trypanosoma cruzi]]
[[Category: Trypanosoma cruzi]]
[[Category: Chattopadhyay, D.]]
[[Category: Chattopadhyay, D.]]

Revision as of 19:47, 25 July 2012

File:3kjs.png

Template:STRUCTURE 3kjs

Crystal Structure of T. cruzi DHFR-TS with 3 high affinity DHFR inhibitors: DQ1 inhibitor complex

Template:ABSTRACT PUBMED 20452776

About this Structure

3kjs is a 4 chain structure of Dihydrofolate reductase and Thymidylate synthase with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.

See Also

Reference

  1. Schormann N, Velu SE, Murugesan S, Senkovich O, Walker K, Chenna BC, Shinkre B, Desai A, Chattopadhyay D. Synthesis and characterization of potent inhibitors of Trypanosoma cruzi dihydrofolate reductase. Bioorg Med Chem. 2010 Jun 1;18(11):4056-66. Epub 2010 Apr 9. PMID:20452776 doi:10.1016/j.bmc.2010.04.020

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