3b2r: Difference between revisions
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Revision as of 20:15, 25 July 2012
Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil
Template:ABSTRACT PUBMED 17959709
About this Structure
3b2r is a 2 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wang H, Ye M, Robinson H, Francis SH, Ke H. Conformational variations of both phosphodiesterase-5 and inhibitors provide the structural basis for the physiological effects of vardenafil and sildenafil. Mol Pharmacol. 2008 Jan;73(1):104-10. Epub 2007 Oct 24. PMID:17959709 doi:10.1124/mol.107.040212
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- 3',5'-cyclic-GMP phosphodiesterase
- Homo sapiens
- Hengming, K.
- Howard, R.
- Huanchen, W.
- Mengchun, Y.
- Sharron, H F.
- Allosteric enzyme
- Cgmp phosphodiesterase
- Cgmp-binding
- Hydrolase
- Levitratm.
- Magnesium
- Metal-binding
- Nucleotide-binding
- Pde5-inhibitor potency
- Phosphorylation
- Sildenafil
- Vardenafil
