2c8x: Difference between revisions

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[[Image:2c8x.png|left|200px]]
[[Image:2c8x.png|left|200px]]


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{{STRUCTURE_2c8x|  PDB=2c8x  |  SCENE=  }}  
{{STRUCTURE_2c8x|  PDB=2c8x  |  SCENE=  }}  


===THROMBIN INHIBITORS===
===THROMBIN INHIBITORS===


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{{ABSTRACT_PUBMED_16480269}}
{{ABSTRACT_PUBMED_16480269}}


==About this Structure==
==About this Structure==
[[2c8x]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C8X OCA].  
[[2c8x]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C8X OCA].  


==See Also==
==See Also==
*[[Hirudin]]
*[[Hirudin|Hirudin]]
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:16480269</ref><references group="xtra"/>
<ref group="xtra">PMID:016480269</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Gamma-carboxyglutamic acid]]
[[Category: Gamma-carboxyglutamic acid]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Kringle]]
[[Category: Kringle]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Serine protea]]
[[Category: Serine protease]]
[[Category: Thrombin]]
[[Category: Thrombin]]

Revision as of 21:26, 25 July 2012

File:2c8x.png

Template:STRUCTURE 2c8x

THROMBIN INHIBITORS

Template:ABSTRACT PUBMED 16480269

About this Structure

2c8x is a 3 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Howard N, Abell C, Blakemore W, Chessari G, Congreve M, Howard S, Jhoti H, Murray CW, Seavers LC, van Montfort RL. Application of fragment screening and fragment linking to the discovery of novel thrombin inhibitors. J Med Chem. 2006 Feb 23;49(4):1346-55. PMID:16480269 doi:10.1021/jm050850v

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