3apc: Difference between revisions

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[[Image:3apc.jpg|left|200px]]
[[Image:3apc.png|left|200px]]


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{{STRUCTURE_3apc|  PDB=3apc  |  SCENE=  }}  
{{STRUCTURE_3apc|  PDB=3apc  |  SCENE=  }}  


===Crystal structure of human PI3K-gamma in complex with CH5132799===
===Crystal structure of human PI3K-gamma in complex with CH5132799===


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{{ABSTRACT_PUBMED_21316229}}
{{ABSTRACT_PUBMED_21316229}}


==About this Structure==
==About this Structure==
[[3apc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3APC OCA].  
[[3apc]] is a 1 chain structure of [[Phosphatidylinositol-4%2C5-bisphosphate 3-kinase]] and [[Phosphoinositide 3-Kinases]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3APC OCA].  
 
==See Also==
*[[Phosphatidylinositol-4%2C5-bisphosphate 3-kinase|Phosphatidylinositol-4%2C5-bisphosphate 3-kinase]]
*[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]]


==Reference==
==Reference==
<ref group="xtra">PMID:21316229</ref><references group="xtra"/>
<ref group="xtra">PMID:021316229</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
Line 29: Line 22:
[[Category: Nakamura, M.]]
[[Category: Nakamura, M.]]
[[Category: Yoshida, M.]]
[[Category: Yoshida, M.]]
[[Category: Kinase]]
[[Category: Phosphoinositide 3-kinase gamma]]
[[Category: Transferase]]
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 21:33, 25 July 2012

File:3apc.png

Template:STRUCTURE 3apc

Crystal structure of human PI3K-gamma in complex with CH5132799

Template:ABSTRACT PUBMED 21316229

About this Structure

3apc is a 1 chain structure of Phosphatidylinositol-4,5-bisphosphate 3-kinase and Phosphoinositide 3-Kinases with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Ohwada J, Ebiike H, Kawada H, Tsukazaki M, Nakamura M, Miyazaki T, Morikami K, Yoshinari K, Yoshida M, Kondoh O, Kuramoto S, Ogawa K, Aoki Y, Shimma N. Discovery and biological activity of a novel class I PI3K inhibitor, CH5132799. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1767-72. Epub 2011 Jan 22. PMID:21316229 doi:10.1016/j.bmcl.2011.01.065

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