3g0f: Difference between revisions

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{{Seed}}
[[Image:3g0f.png|left|200px]]
[[Image:3g0f.png|left|200px]]


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{{STRUCTURE_3g0f|  PDB=3g0f  |  SCENE=  }}  
{{STRUCTURE_3g0f|  PDB=3g0f  |  SCENE=  }}  


===KIT kinase domain mutant D816H in complex with sunitinib===
===KIT kinase domain mutant D816H in complex with sunitinib===


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{{ABSTRACT_PUBMED_19164557}}
{{ABSTRACT_PUBMED_19164557}}


==Disease==
==About this Structure==
Known disease associated with this structure: Gastrointestinal stromal tumor, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Germ cell tumors OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Leukemia, acute myeloid OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Mast cell leukemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Mastocytosis with associated hematologic disorder OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Piebaldism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]]
[[3g0f]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G0F OCA].  


==About this Structure==
==See Also==
3G0F is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G0F OCA].
*[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:19164557</ref><references group="xtra"/>
<ref group="xtra">PMID:019164557</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Proto-oncogene]]
[[Category: Proto-oncogene]]
[[Category: Receptor]]
[[Category: Receptor]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun  3 10:20:33 2009''