2viy: Difference between revisions

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{{Seed}}
[[Image:2viy.png|left|200px]]
[[Image:2viy.png|left|200px]]


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{{STRUCTURE_2viy|  PDB=2viy  |  SCENE=  }}  
{{STRUCTURE_2viy|  PDB=2viy  |  SCENE=  }}  


===HUMAN BACE-1 IN COMPLEX WITH N-((1S,2R)-3-(((1S)-2-(CYCLOHEXYLAMINO)-1-METHYL-2-OXOETHYL)AMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL)-3-(PENTYLSULFONYL)BENZAMIDE===
===HUMAN BACE-1 IN COMPLEX WITH N-((1S,2R)-3-(((1S)-2-(CYCLOHEXYLAMINO)-1-METHYL-2-OXOETHYL)AMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL)-3-(PENTYLSULFONYL)BENZAMIDE===


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{{ABSTRACT_PUBMED_18171614}}
{{ABSTRACT_PUBMED_18171614}}


==About this Structure==
==About this Structure==
2VIY is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VIY OCA].  
[[2viy]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VIY OCA].  
 
==See Also==
*[[Beta secretase|Beta secretase]]


==Reference==
==Reference==
<ref group="xtra">PMID:18171614</ref><references group="xtra"/>
<ref group="xtra">PMID:018171614</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
Line 53: Line 44:
[[Category: Ward, J.]]
[[Category: Ward, J.]]
[[Category: Wayne, G.]]
[[Category: Wayne, G.]]
[[Category: Alternative splicing]]
[[Category: Asp-2]]
[[Category: Asp-2]]
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
Line 66: Line 56:
[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:22:37 2009''

Revision as of 22:57, 25 July 2012

File:2viy.png

Template:STRUCTURE 2viy

HUMAN BACE-1 IN COMPLEX WITH N-((1S,2R)-3-(((1S)-2-(CYCLOHEXYLAMINO)-1-METHYL-2-OXOETHYL)AMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL)-3-(PENTYLSULFONYL)BENZAMIDE

Template:ABSTRACT PUBMED 18171614

About this Structure

2viy is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Clarke B, Demont E, Dingwall C, Dunsdon R, Faller A, Hawkins J, Hussain I, MacPherson D, Maile G, Matico R, Milner P, Mosley J, Naylor A, O'Brien A, Redshaw S, Riddell D, Rowland P, Soleil V, Smith KJ, Stanway S, Stemp G, Sweitzer S, Theobald P, Vesey D, Walter DS, Ward J, Wayne G. BACE-1 inhibitors part 1: identification of novel hydroxy ethylamines (HEAs). Bioorg Med Chem Lett. 2008 Feb 1;18(3):1011-6. Epub 2007 Dec 15. PMID:18171614 doi:https://dx.doi.org/10.1016/j.bmcl.2007.12.017

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