3e4a: Difference between revisions
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Revision as of 23:12, 25 July 2012
Human IDE-inhibitor complex at 2.6 angstrom resolution
Template:ABSTRACT PUBMED 20498699
About this Structure
3e4a is a 4 chain structure of Insulin-Degrading Enzyme with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Leissring MA, Malito E, Hedouin S, Reinstatler L, Sahara T, Abdul-Hay SO, Choudhry S, Maharvi GM, Fauq AH, Huzarska M, May PS, Choi S, Logan TP, Turk BE, Cantley LC, Manolopoulou M, Tang WJ, Stein RL, Cuny GD, Selkoe DJ. Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin. PLoS One. 2010 May 7;5(5):e10504. PMID:20498699 doi:10.1371/journal.pone.0010504