1hwk: Difference between revisions

Revision as of 23:34, 25 July 2012

1hwk is a 4 chain structure of HMG-CoA Reductase with sequence from Homo sapiens. The December 2007 RCSB PDB Molecule of the Month feature on Oxidosqualene Cyclase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2007_12. Full crystallographic information is available from OCA.

Istvan ES, Deisenhofer J. Structural mechanism for statin inhibition of HMG-CoA reductase. Science. 2001 May 11;292(5519):1160-4. PMID:11349148 doi:10.1126/science.1059344

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 [[Image:1hwk.png|left|200px]]
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 ===COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH ATORVASTATIN===
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