3f19: Difference between revisions

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[[Image:3f19.png|left|200px]]
[[Image:3f19.png|left|200px]]


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{{STRUCTURE_3f19|  PDB=3f19  |  SCENE=  }}  
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===Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor 4-fluoro-N-(2-nitroso-2-oxoethyl)benzenesulfonamide===
===Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor 4-fluoro-N-(2-nitroso-2-oxoethyl)benzenesulfonamide===


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{{ABSTRACT_PUBMED_17269766}}


==About this Structure==
==About this Structure==
[[3f19]] is a 1 chain structure of [[Elastase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F19 OCA].  
[[3f19]] is a 1 chain structure of [[Elastase]] and [[Matrix metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F19 OCA].  


==See Also==
==See Also==
*[[Elastase]]
*[[Elastase|Elastase]]
*[[Matrix metalloproteinase|Matrix metalloproteinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:17269766</ref><ref group="xtra">PMID:12813751</ref><references group="xtra"/>
<ref group="xtra">PMID:017269766</ref><ref group="xtra">PMID:012813751</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Calderone, V.]]
[[Category: Calderone, V.]]
[[Category: Calcium]]
[[Category: Elastase]]
[[Category: Elastase]]
[[Category: Extracellular matrix]]
[[Category: Extracellular matrix]]
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[[Category: Metalloprotease]]
[[Category: Metalloprotease]]
[[Category: Mmp12]]
[[Category: Mmp12]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Secreted]]
[[Category: Zinc]]
[[Category: Zymogen]]
[[Category: Zymogen]]

Revision as of 23:58, 25 July 2012

File:3f19.png

Template:STRUCTURE 3f19

Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor 4-fluoro-N-(2-nitroso-2-oxoethyl)benzenesulfonamide

Template:ABSTRACT PUBMED 17269766

About this Structure

3f19 is a 1 chain structure of Elastase and Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Bertini I, Calderone V, Fragai M, Giachetti A, Loconte M, Luchinat C, Maletta M, Nativi C, Yeo KJ. Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases. J Am Chem Soc. 2007 Mar 7;129(9):2466-75. Epub 2007 Feb 2. PMID:17269766 doi:10.1021/ja065156z
  2. Bertini I, Calderone V, Fragai M, Luchinat C, Mangani S, Terni B. X-ray structures of binary and ternary enzyme-product-inhibitor complexes of matrix metalloproteinases. Angew Chem Int Ed Engl. 2003 Jun 16;42(23):2673-6. PMID:12813751 doi:10.1002/anie.200350957

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