2a2q: Difference between revisions

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{{Seed}}
[[Image:2a2q.png|left|200px]]
[[Image:2a2q.png|left|200px]]


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{{STRUCTURE_2a2q|  PDB=2a2q  |  SCENE=  }}  
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===Complex of Active-site Inhibited Human Coagulation Factor VIIa with Human Soluble Tissue Factor in the Presence of Ca2+, Mg2+, Na+, and Zn2+===
===Complex of Active-site Inhibited Human Coagulation Factor VIIa with Human Soluble Tissue Factor in the Presence of Ca2+, Mg2+, Na+, and Zn2+===


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{{ABSTRACT_PUBMED_16757484}}
{{ABSTRACT_PUBMED_16757484}}


==Disease==
==About this Structure==
Known disease associated with this structure: Factor VII deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Myocardial infarction, decreased susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]]
[[2a2q]] is a 3 chain structure of [[Factor VIIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A2Q OCA].


==About this Structure==
==See Also==
2A2Q is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A2Q OCA].
*[[Factor VIIa|Factor VIIa]]


==Reference==
==Reference==
<ref group="xtra">PMID:16757484</ref><references group="xtra"/>
<ref group="xtra">PMID:016757484</ref><references group="xtra"/>
[[Category: Coagulation factor VIIa]]
[[Category: Coagulation factor VIIa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Ca2+]]
[[Category: Ca2+]]
[[Category: Factor viia]]
[[Category: Factor viia]]
[[Category: Hydrolase-blood clotting complex]]
[[Category: Mg2+]]
[[Category: Mg2+]]
[[Category: Na+]]
[[Category: Na+]]
[[Category: Soluble tissue factor]]
[[Category: Soluble tissue factor]]
[[Category: Zn2+]]
[[Category: Zn2+]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:30:30 2009''

Revision as of 00:24, 26 July 2012

File:2a2q.png

Template:STRUCTURE 2a2q

Complex of Active-site Inhibited Human Coagulation Factor VIIa with Human Soluble Tissue Factor in the Presence of Ca2+, Mg2+, Na+, and Zn2+

Template:ABSTRACT PUBMED 16757484

About this Structure

2a2q is a 3 chain structure of Factor VIIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Bajaj SP, Schmidt AE, Agah S, Bajaj MS, Padmanabhan K. High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa. J Biol Chem. 2006 Aug 25;281(34):24873-88. Epub 2006 Jun 6. PMID:16757484 doi:10.1074/jbc.M509971200

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