3s2o: Difference between revisions
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[[Image:3s2o.png|left|200px]] | [[Image:3s2o.png|left|200px]] | ||
{{STRUCTURE_3s2o| PDB=3s2o | SCENE= }} | {{STRUCTURE_3s2o| PDB=3s2o | SCENE= }} | ||
===Fragment based discovery and optimisation of bace-1 inhibitors=== | ===Fragment based discovery and optimisation of bace-1 inhibitors=== | ||
{{ABSTRACT_PUBMED_20656487}} | {{ABSTRACT_PUBMED_20656487}} | ||
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==See Also== | ==See Also== | ||
*[[Beta secretase]] | *[[Beta secretase|Beta secretase]] | ||
==Reference== | ==Reference== | ||
Revision as of 00:53, 26 July 2012
Fragment based discovery and optimisation of bace-1 inhibitors
Template:ABSTRACT PUBMED 20656487
About this Structure
3s2o is a 1 chain structure of Beta secretase with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3msm. Full crystallographic information is available from OCA.
See Also
Reference
- Madden J, Dod JR, Godemann R, Kraemer J, Smith M, Biniszkiewicz M, Hallett DJ, Barker J, Dyekjaer JD, Hesterkamp T. Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5329-33. Epub 2010 Jun 27. PMID:20656487 doi:10.1016/j.bmcl.2010.06.089
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Memapsin 2
- Barker, J.
- Godemann, R.
- Hallett, D.
- Kraemer, J.
- Madden, J.
- Smith, M A.
- Alzheimer's disease
- Amyloid precursor protein secretase
- Aspartic endopeptidase
- Aspartic protease
- Aspartyl protease
- Base
- Beta-secretase
- Fluorescence polarisation
- Fragment-based drug design
- Glycoprotein
- Hydrolase-hydrolase inhibitor complex
- Protease
- Transmembrane
