1cj5: Difference between revisions

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[[Image:1cj5.gif|left|200px]]<br /><applet load="1cj5" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1cj5.gif|left|200px]]<br /><applet load="1cj5" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1cj5" />

'''BOVINE BETA-LACTOGLOBULIN A'''<br />

==Overview==

Using heteronuclear NMR spectroscopy, we studied the solution structure, and dynamics of bovine beta-lactoglobulin A at pH 2.0 and 45 degrees C, where the protein exists as a monomeric native state. The monomeric NMR, structure, comprising an eight-stranded continuous antiparallel, beta-barrel and one major alpha-helix, is similar to the X-ray dimeric, structure obtained at pH 6.2, including betaI-strand that forms the dimer, interface and loop EF that serves as a lid of the interior hydrophobic, hole. [1H]-15N NOE revealed that betaF, betaG, and betaH strands buried, under the major alpha-helix are rigid on a pico- to nanosecond time scale, and also emphasized rapid fluctuations of loops and the N- and C-terminal, regions.

Using heteronuclear NMR spectroscopy, we studied the solution structure and dynamics of bovine beta-lactoglobulin A at pH 2.0 and 45 degrees C, where the protein exists as a monomeric native state. The monomeric NMR structure, comprising an eight-stranded continuous antiparallel beta-barrel and one major alpha-helix, is similar to the X-ray dimeric structure obtained at pH 6.2, including betaI-strand that forms the dimer interface and loop EF that serves as a lid of the interior hydrophobic hole. [1H]-15N NOE revealed that betaF, betaG, and betaH strands buried under the major alpha-helix are rigid on a pico- to nanosecond time scale and also emphasized rapid fluctuations of loops and the N- and C-terminal regions.

==About this Structure==

1CJ5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1CJ5 OCA].

1CJ5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CJ5 OCA].

==Reference==

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[[Category: Bos taurus]]

[[Category: Single protein]]

[[Category: Batt, C.A.]]

[[Category: Batt, C A.]]

[[Category: Era, S.]]

[[Category: Forge, V.]]

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[[Category: dynamics]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Tue Nov 20~~ 12:30:~~32 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:06:41 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1cj5.gif|left|200px]]<br /><applet load="1cj5" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1cj5.gif|left|200px]]<br /><applet load="1cj5" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1cj5" />
 '''BOVINE BETA-LACTOGLOBULIN A'''<br />
 ==Overview==
-Using heteronuclear NMR spectroscopy, we studied the solution structure, and dynamics of bovine beta-lactoglobulin A at pH 2.0 and 45 degrees C, where the protein exists as a monomeric native state. The monomeric NMR, structure, comprising an eight-stranded continuous antiparallel, beta-barrel and one major alpha-helix, is similar to the X-ray dimeric, structure obtained at pH 6.2, including betaI-strand that forms the dimer, interface and loop EF that serves as a lid of the interior hydrophobic, hole. [1H]-15N NOE revealed that betaF, betaG, and betaH strands buried, under the major alpha-helix are rigid on a pico- to nanosecond time scale, and also emphasized rapid fluctuations of loops and the N- and C-terminal, regions.
+Using heteronuclear NMR spectroscopy, we studied the solution structure and dynamics of bovine beta-lactoglobulin A at pH 2.0 and 45 degrees C, where the protein exists as a monomeric native state. The monomeric NMR structure, comprising an eight-stranded continuous antiparallel beta-barrel and one major alpha-helix, is similar to the X-ray dimeric structure obtained at pH 6.2, including betaI-strand that forms the dimer interface and loop EF that serves as a lid of the interior hydrophobic hole. [1H]-15N NOE revealed that betaF, betaG, and betaH strands buried under the major alpha-helix are rigid on a pico- to nanosecond time scale and also emphasized rapid fluctuations of loops and the N- and C-terminal regions.
 ==About this Structure==
-CJ5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1CJ5 OCA].
+CJ5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CJ5 OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Bos taurus]]
 [[Category: Single protein]]
-[[Category: Batt, C.A.]]
+[[Category: Batt, C A.]]
 [[Category: Era, S.]]
 [[Category: Forge, V.]]
@@ Line 22: / Line 22: @@
 [[Category: dynamics]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 12:30:32 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:06:41 2008''