2va6: Difference between revisions
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Revision as of 01:45, 26 July 2012
X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 24
Template:ABSTRACT PUBMED 17985862
About this Structure
2va6 is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Edwards PD, Albert JS, Sylvester M, Aharony D, Andisik D, Callaghan O, Campbell JB, Carr RA, Chessari G, Congreve M, Frederickson M, Folmer RH, Geschwindner S, Koether G, Kolmodin K, Krumrine J, Mauger RC, Murray CW, Olsson LL, Patel S, Spear N, Tian G. Application of fragment-based lead generation to the discovery of novel, cyclic amidine beta-secretase inhibitors with nanomolar potency, cellular activity, and high ligand efficiency. J Med Chem. 2007 Nov 29;50(24):5912-25. Epub 2007 Nov 7. PMID:17985862 doi:https://dx.doi.org/10.1021/jm070829p
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Memapsin 2
- Aharony, D.
- Albert, J S.
- Andisik, D.
- Callaghan, O.
- Campbell, J B.
- Carr, R A.
- Chessari, G.
- Congreve, M.
- Edwards, P D.
- Folmer, R H.A.
- Frederickson, M.
- Geschwindner, S.
- Koether, G.
- Kolmodin, K.
- Krumrine, J.
- Mauger, R C.
- Murray, C W.
- Olsson, L L.
- Patel, S.
- Spear, N.
- Sylvester, M.
- Tian, G.
- Alzheimer's disease
- Aspartic protease
- Aspartyl protease
- Base
- Beta-secretase
- Glycoprotein
- Hydrolase
- Membrane
- Protease
- Transmembrane
- Zymogen
