1nwe: Difference between revisions

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{{Seed}}
[[Image:1nwe.png|left|200px]]
[[Image:1nwe.png|left|200px]]


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{{STRUCTURE_1nwe|  PDB=1nwe  |  SCENE=  }}  
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===Ptp1B R47C Modified at C47 with N-[4-(2-{2-[3-(2-Bromo-acetylamino)-propionylamino]-3-hydroxy-propionylamino}-ethyl)-phenyl]-oxalamic acid===
===Ptp1B R47C Modified at C47 with N-[4-(2-{2-[3-(2-Bromo-acetylamino)-propionylamino]-3-hydroxy-propionylamino}-ethyl)-phenyl]-oxalamic acid===


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{{ABSTRACT_PUBMED_12733877}}
{{ABSTRACT_PUBMED_12733877}}


==Disease==
==About this Structure==
Known disease associated with this structure: Insulin resistance, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176885 176885]]
[[1nwe]] is a 1 chain structure of [[Proten tyrosine phosphatase]] and [[Tyrosine phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NWE OCA].


==About this Structure==
==See Also==
1NWE is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NWE OCA].
*[[Proten tyrosine phosphatase|Proten tyrosine phosphatase]]
*[[Tyrosine phosphatase|Tyrosine phosphatase]]


==Reference==
==Reference==
<ref group="xtra">PMID:12733877</ref><references group="xtra"/>
<ref group="xtra">PMID:012733877</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Protein-tyrosine-phosphatase]]
Line 37: Line 26:
[[Category: Simmons, R L.]]
[[Category: Simmons, R L.]]
[[Category: Waight, A.]]
[[Category: Waight, A.]]
[[Category: Acetylation]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Phospatase]]
[[Category: Phospatase]]
[[Category: Phosphorylation]]
[[Category: Phosphorylation]]
[[Category: Phosphotyrosine mimetic]]
[[Category: Phosphotyrosine mimetic]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:03:31 2009''

Revision as of 01:51, 26 July 2012

File:1nwe.png

Template:STRUCTURE 1nwe

Ptp1B R47C Modified at C47 with N-[4-(2-{2-[3-(2-Bromo-acetylamino)-propionylamino]-3-hydroxy-propionylamino}-ethyl)-phenyl]-oxalamic acid

Template:ABSTRACT PUBMED 12733877

About this Structure

1nwe is a 1 chain structure of Proten tyrosine phosphatase and Tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Erlanson DA, McDowell RS, He MM, Randal M, Simmons RL, Kung J, Waight A, Hansen SK. Discovery of a new phosphotyrosine mimetic for PTP1B using breakaway tethering. J Am Chem Soc. 2003 May 14;125(19):5602-3. PMID:12733877 doi:10.1021/ja034440c

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