2qhm: Difference between revisions

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{{Seed}}
[[Image:2qhm.png|left|200px]]
[[Image:2qhm.png|left|200px]]


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{{STRUCTURE_2qhm|  PDB=2qhm  |  SCENE=  }}  
{{STRUCTURE_2qhm|  PDB=2qhm  |  SCENE=  }}  


===crystal structure of Chek1 in complex with inhibitor 2a===
===crystal structure of Chek1 in complex with inhibitor 2a===


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{{ABSTRACT_PUBMED_17804227}}
{{ABSTRACT_PUBMED_17804227}}


==About this Structure==
==About this Structure==
2QHM is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QHM OCA].  
[[2qhm]] is a 1 chain structure of [[Serine/threonine protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QHM OCA].  
 
==See Also==
*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:17804227</ref><references group="xtra"/>
<ref group="xtra">PMID:017804227</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Kinase]]
[[Category: Kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:12:47 2009''

Revision as of 01:55, 26 July 2012

File:2qhm.png

Template:STRUCTURE 2qhm

crystal structure of Chek1 in complex with inhibitor 2a

Template:ABSTRACT PUBMED 17804227

About this Structure

2qhm is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Brnardic EJ, Garbaccio RM, Fraley ME, Tasber ES, Steen JT, Arrington KL, Dudkin VY, Hartman GD, Stirdivant SM, Drakas BA, Rickert K, Walsh ES, Hamilton K, Buser CA, Hardwick J, Tao W, Beck SC, Mao X, Lobell RB, Sepp-Lorenzino L, Yan Y, Ikuta M, Munshi SK, Kuo LC, Kreatsoulas C. Optimization of a pyrazoloquinolinone class of Chk1 kinase inhibitors. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5989-94. Epub 2007 Aug 19. PMID:17804227 doi:10.1016/j.bmcl.2007.07.051

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