3lpi: Difference between revisions

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Revision as of 02:09, 26 July 2012

File:3lpi.png

Template:STRUCTURE 3lpi

Structure of BACE Bound to SCH745132

Template:ABSTRACT PUBMED 20347593

About this Structure

3lpi is a 2 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Cumming J, Babu S, Huang Y, Carrol C, Chen X, Favreau L, Greenlee W, Guo T, Kennedy M, Kuvelkar R, Le T, Li G, McHugh N, Orth P, Ozgur L, Parker E, Saionz K, Stamford A, Strickland C, Tadesse D, Voigt J, Zhang L, Zhang Q. Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterization. Bioorg Med Chem Lett. 2010 May 1;20(9):2837-42. Epub 2010 Mar 12. PMID:20347593 doi:10.1016/j.bmcl.2010.03.050

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