3oc0: Difference between revisions
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[[Image:3oc0.png|left|200px]] | [[Image:3oc0.png|left|200px]] | ||
{{STRUCTURE_3oc0| PDB=3oc0 | SCENE= }} | {{STRUCTURE_3oc0| PDB=3oc0 | SCENE= }} | ||
===Structure of human DPP-IV with HTS hit (2S,3S,11bS)-3-butyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ylamine=== | ===Structure of human DPP-IV with HTS hit (2S,3S,11bS)-3-butyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ylamine=== | ||
{{ABSTRACT_PUBMED_20031405}} | {{ABSTRACT_PUBMED_20031405}} | ||
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==See Also== | ==See Also== | ||
*[[Dipeptidyl peptidase]] | *[[Dipeptidyl peptidase|Dipeptidyl peptidase]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020031405</ref><references group="xtra"/> | ||
[[Category: Dipeptidyl-peptidase IV]] | [[Category: Dipeptidyl-peptidase IV]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
Revision as of 02:16, 26 July 2012
Structure of human DPP-IV with HTS hit (2S,3S,11bS)-3-butyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ylamine
Template:ABSTRACT PUBMED 20031405
About this Structure
3oc0 is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3kwh. Full crystallographic information is available from OCA.
See Also
Reference
- Mattei P, Boehringer M, Di Giorgio P, Fischer H, Hennig M, Huwyler J, Kocer B, Kuhn B, Loeffler BM, Macdonald A, Narquizian R, Rauber E, Sebokova E, Sprecher U. Discovery of carmegliptin: a potent and long-acting dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1109-13. Epub 2009 Dec 6. PMID:20031405 doi:10.1016/j.bmcl.2009.12.024
