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[[Image:3dll.png|left|200px]]
[[Image:3dll.png|left|200px]]


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{{STRUCTURE_3dll|  PDB=3dll  |  SCENE=  }}  
{{STRUCTURE_3dll|  PDB=3dll  |  SCENE=  }}  


===The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning===
===The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning===


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{{ABSTRACT_PUBMED_18757750}}
{{ABSTRACT_PUBMED_18757750}}


==About this Structure==
==About this Structure==
[[3dll]] is a 30 chain structure of [[Ribosomal protein L2]], [[Ribosomal protein L3]], [[Ribosomal protein L4]], [[Ribosomal protein L5]], [[Ribosomal protein L6]] and [[Ribosome]] with sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DLL OCA].  
[[3dll]] is a 30 chain structure of [[Ribosomal protein L11]], [[Ribosomal protein L13]], [[Ribosomal protein L14]], [[Ribosomal protein L15]], [[Ribosomal protein L16]], [[Ribosomal protein L17]], [[Ribosomal protein L18]], [[Ribosomal protein L19]], [[Ribosomal protein L2]], [[Ribosomal protein L20]], [[Ribosomal protein L21]], [[Ribosomal protein L22]], [[Ribosomal protein L23]], [[Ribosomal protein L24]], [[Ribosomal protein L25]], [[Ribosomal protein L27]], [[Ribosomal protein L28]], [[Ribosomal protein L29]], [[Ribosomal protein L3]], [[Ribosomal protein L30]], [[Ribosomal protein L32]], [[Ribosomal protein L33]], [[Ribosomal protein L34]], [[Ribosomal protein L35]], [[Ribosomal protein L36]], [[Ribosomal protein L4]], [[Ribosomal protein L5]], [[Ribosomal protein L6]] and [[Ribosome]] with sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DLL OCA].  


==See Also==
==See Also==
*[[Ribosomal protein L2]]
*[[Ribosomal protein L11|Ribosomal protein L11]]
*[[Ribosomal protein L3]]
*[[Ribosomal protein L13|Ribosomal protein L13]]
*[[Ribosomal protein L4]]
*[[Ribosomal protein L14|Ribosomal protein L14]]
*[[Ribosomal protein L5]]
*[[Ribosomal protein L15|Ribosomal protein L15]]
*[[Ribosomal protein L6]]
*[[Ribosomal protein L16|Ribosomal protein L16]]
*[[Ribosome]]
*[[Ribosomal protein L17|Ribosomal protein L17]]
*[[Ribosomal protein L18|Ribosomal protein L18]]
*[[Ribosomal protein L19|Ribosomal protein L19]]
*[[Ribosomal protein L2|Ribosomal protein L2]]
*[[Ribosomal protein L20|Ribosomal protein L20]]
*[[Ribosomal protein L21|Ribosomal protein L21]]
*[[Ribosomal protein L22|Ribosomal protein L22]]
*[[Ribosomal protein L23|Ribosomal protein L23]]
*[[Ribosomal protein L24|Ribosomal protein L24]]
*[[Ribosomal protein L25|Ribosomal protein L25]]
*[[Ribosomal protein L27|Ribosomal protein L27]]
*[[Ribosomal protein L28|Ribosomal protein L28]]
*[[Ribosomal protein L29|Ribosomal protein L29]]
*[[Ribosomal protein L3|Ribosomal protein L3]]
*[[Ribosomal protein L30|Ribosomal protein L30]]
*[[Ribosomal protein L32|Ribosomal protein L32]]
*[[Ribosomal protein L33|Ribosomal protein L33]]
*[[Ribosomal protein L34|Ribosomal protein L34]]
*[[Ribosomal protein L35|Ribosomal protein L35]]
*[[Ribosomal protein L36|Ribosomal protein L36]]
*[[Ribosomal protein L4|Ribosomal protein L4]]
*[[Ribosomal protein L5|Ribosomal protein L5]]
*[[Ribosomal protein L6|Ribosomal protein L6]]
*[[Ribosome|Ribosome]]


==Reference==
==Reference==
<ref group="xtra">PMID:18757750</ref><references group="xtra"/>
<ref group="xtra">PMID:018757750</ref><references group="xtra"/>
[[Category: Deinococcus radiodurans]]
[[Category: Deinococcus radiodurans]]
[[Category: Connell, S R.]]
[[Category: Connell, S R.]]
Line 49: Line 61:
[[Category: Rrna-binding]]
[[Category: Rrna-binding]]
[[Category: Trna-binding]]
[[Category: Trna-binding]]
[[Category: Zinc]]
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]

Revision as of 02:44, 26 July 2012

File:3dll.png

Template:STRUCTURE 3dll

The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning

Template:ABSTRACT PUBMED 18757750

About this Structure

3dll is a 30 chain structure of Ribosomal protein L11, Ribosomal protein L13, Ribosomal protein L14, Ribosomal protein L15, Ribosomal protein L16, Ribosomal protein L17, Ribosomal protein L18, Ribosomal protein L19, Ribosomal protein L2, Ribosomal protein L20, Ribosomal protein L21, Ribosomal protein L22, Ribosomal protein L23, Ribosomal protein L24, Ribosomal protein L25, Ribosomal protein L27, Ribosomal protein L28, Ribosomal protein L29, Ribosomal protein L3, Ribosomal protein L30, Ribosomal protein L32, Ribosomal protein L33, Ribosomal protein L34, Ribosomal protein L35, Ribosomal protein L36, Ribosomal protein L4, Ribosomal protein L5, Ribosomal protein L6 and Ribosome with sequence from Deinococcus radiodurans. Full crystallographic information is available from OCA.

See Also

Reference

  1. Wilson DN, Schluenzen F, Harms JM, Starosta AL, Connell SR, Fucini P. The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13339-44. Epub 2008 Aug 29. PMID:18757750

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