3pj8: Difference between revisions

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[[Image:3pj8.png|left|200px]]
[[Image:3pj8.png|left|200px]]


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{{STRUCTURE_3pj8|  PDB=3pj8  |  SCENE=  }}  
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===Structure of CDK2 in complex with a Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine.===
===Structure of CDK2 in complex with a Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine.===


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{{ABSTRACT_PUBMED_21417417}}
{{ABSTRACT_PUBMED_21417417}}


==About this Structure==
==About this Structure==
[[3pj8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJ8 OCA].  
[[3pj8]] is a 1 chain structure of [[Cell Division Protein Kinase 2]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJ8 OCA].  
 
==See Also==
*[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]]


==Reference==
==Reference==
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[[Category: Voller, J.]]
[[Category: Voller, J.]]
[[Category: Walkinshaw, M D.]]
[[Category: Walkinshaw, M D.]]
[[Category: Cell division]]
[[Category: Cyclin]]
[[Category: Mitosis]]
[[Category: Phosphorylation]]
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 03:41, 26 July 2012

File:3pj8.png

Template:STRUCTURE 3pj8

Structure of CDK2 in complex with a Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine.

Template:ABSTRACT PUBMED 21417417

About this Structure

3pj8 is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Jorda R, Havlicek L, McNae IW, Walkinshaw MD, Voller J, Sturc A, Navratilova J, Kuzma M, Mistrik M, Bartek J, Strnad M, Krystof V. Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-dependent Kinases with Antiproliferative Activity. J Med Chem. 2011 Mar 21. PMID:21417417 doi:10.1021/jm200064p

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