3msk: Difference between revisions

Revision as of 03:48, 26 July 2012

3msk is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Madden J, Dod JR, Godemann R, Kraemer J, Smith M, Biniszkiewicz M, Hallett DJ, Barker J, Dyekjaer JD, Hesterkamp T. Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5329-33. Epub 2010 Jun 27. PMID:20656487 doi:10.1016/j.bmcl.2010.06.089

@@ Line 1: / Line 1: @@
 [[Image:3msk.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3msk", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_3msk|  PDB=3msk  |  SCENE=  }}
 ===Fragment Based Discovery and Optimisation of BACE-1 Inhibitors===
-<!--
-The line below this paragraph, {{ABSTRACT_PUBMED_20656487}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 20656487 is the PubMed ID number.
--->
 {{ABSTRACT_PUBMED_20656487}}
@@ Line 22: / Line 11: @@
 ==See Also==
-*[[Beta secretase]]
+*[[Beta secretase|Beta secretase]]
 ==Reference==
@@ Line 34: / Line 23: @@
 [[Category: Madden, J M.]]
 [[Category: Smith, M A]]
+[[Category: Alzheimer's disease]]
+[[Category: Amyloid precursor protein secretase]]
+[[Category: Aspartic endopeptidase]]
+[[Category: Aspartic protease]]
+[[Category: Aspartyl protease]]
+[[Category: Base]]
+[[Category: Beta-secretase]]
+[[Category: Fluorescence polarisation]]
+[[Category: Fragment-based drug design]]
+[[Category: Glycoprotein]]
+[[Category: Hydrolase]]
+[[Category: Hydrolase-hydrolase inhibitor complex]]
+[[Category: Memapsin 2]]
+[[Category: Protease]]
+[[Category: Transmembrane]]
+[[Category: Zymogen]]