2uxn: Difference between revisions

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[[Image:2uxn.png|left|200px]]
[[Image:2uxn.png|left|200px]]


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{{STRUCTURE_2uxn|  PDB=2uxn  |  SCENE=  }}  
{{STRUCTURE_2uxn|  PDB=2uxn  |  SCENE=  }}  


===STRUCTURAL BASIS OF HISTONE DEMETHYLATION BY LSD1 REVEALED BY SUICIDE INACTIVATION===
===STRUCTURAL BASIS OF HISTONE DEMETHYLATION BY LSD1 REVEALED BY SUICIDE INACTIVATION===


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{{ABSTRACT_PUBMED_17529991}}
{{ABSTRACT_PUBMED_17529991}}


==About this Structure==
==About this Structure==
[[2uxn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXN OCA].  
[[2uxn]] is a 3 chain structure of [[Lysine-specific histone demethylase 1]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXN OCA].  
 
==See Also==
*[[Lysine-specific histone demethylase 1|Lysine-specific histone demethylase 1]]


==Reference==
==Reference==
<ref group="xtra">PMID:17529991</ref><ref group="xtra">PMID:16885027</ref><references group="xtra"/>
<ref group="xtra">PMID:017529991</ref><ref group="xtra">PMID:016885027</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Brautigam, C A.]]
[[Category: Brautigam, C A.]]
Line 33: Line 25:
[[Category: Yang, M.]]
[[Category: Yang, M.]]
[[Category: Yu, H.]]
[[Category: Yu, H.]]
[[Category: Alternative splicing]]
[[Category: Chromatin demethylation]]
[[Category: Chromatin demethylation]]
[[Category: Chromatin regulator]]
[[Category: Chromatin regulator]]
[[Category: Coiled coil]]
[[Category: Corest]]
[[Category: Corest]]
[[Category: Fad]]
[[Category: Fad]]
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[[Category: Nucleosome]]
[[Category: Nucleosome]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase/repressor complex]]
[[Category: Oxidoreductase-repressor complex]]
[[Category: Oxidoreductase/transcription regulator]]
[[Category: Oxidoreductase-transcription regulator complex]]
[[Category: Phosphorylation]]
[[Category: Phosphorylation]]
[[Category: Repressor]]
[[Category: Repressor]]
[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulation]]

Revision as of 03:52, 26 July 2012

File:2uxn.png

Template:STRUCTURE 2uxn

STRUCTURAL BASIS OF HISTONE DEMETHYLATION BY LSD1 REVEALED BY SUICIDE INACTIVATION

Template:ABSTRACT PUBMED 17529991

About this Structure

2uxn is a 3 chain structure of Lysine-specific histone demethylase 1 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Yang M, Culhane JC, Szewczuk LM, Gocke CB, Brautigam CA, Tomchick DR, Machius M, Cole PA, Yu H. Structural basis of histone demethylation by LSD1 revealed by suicide inactivation. Nat Struct Mol Biol. 2007 Jun;14(6):535-9. Epub 2007 May 27. PMID:17529991 doi:https://dx.doi.org/10.1038/nsmb1255
  2. Yang M, Gocke CB, Luo X, Borek D, Tomchick DR, Machius M, Otwinowski Z, Yu H. Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase. Mol Cell. 2006 Aug 4;23(3):377-87. PMID:16885027 doi:https://dx.doi.org/10.1016/j.molcel.2006.07.012

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