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[[Image:1xbp.png|left|200px]]
[[Image:1xbp.png|left|200px]]


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===Inhibition of peptide bond formation by pleuromutilins: The structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with Tiamulin===
===Inhibition of peptide bond formation by pleuromutilins: The structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with Tiamulin===


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{{ABSTRACT_PUBMED_15554968}}
{{ABSTRACT_PUBMED_15554968}}


==About this Structure==
==About this Structure==
[[1xbp]] is a 30 chain structure of [[Ribosomal protein L2]], [[Ribosomal protein L3]], [[Ribosomal protein L4]], [[Ribosomal protein L5]] and [[Ribosomal protein L6]] with sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XBP OCA].  
[[1xbp]] is a 30 chain structure of [[Ribosomal protein L11]], [[Ribosomal protein L13]], [[Ribosomal protein L14]], [[Ribosomal protein L15]], [[Ribosomal protein L16]], [[Ribosomal protein L17]], [[Ribosomal protein L18]], [[Ribosomal protein L19]], [[Ribosomal protein L2]], [[Ribosomal protein L20]], [[Ribosomal protein L21]], [[Ribosomal protein L22]], [[Ribosomal protein L23]], [[Ribosomal protein L24]], [[Ribosomal protein L25]], [[Ribosomal protein L27]], [[Ribosomal protein L29]], [[Ribosomal protein L3]], [[Ribosomal protein L30]], [[Ribosomal protein L31]], [[Ribosomal protein L32]], [[Ribosomal protein L33]], [[Ribosomal protein L34]], [[Ribosomal protein L35]], [[Ribosomal protein L36]], [[Ribosomal protein L4]], [[Ribosomal protein L5]], [[Ribosomal protein L6]] and [[Ribosomal protein L9]] with sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XBP OCA].  


==See Also==
==See Also==
*[[Ribosomal protein L2]]
*[[Ribosomal protein L11|Ribosomal protein L11]]
*[[Ribosomal protein L3]]
*[[Ribosomal protein L13|Ribosomal protein L13]]
*[[Ribosomal protein L4]]
*[[Ribosomal protein L14|Ribosomal protein L14]]
*[[Ribosomal protein L5]]
*[[Ribosomal protein L15|Ribosomal protein L15]]
*[[Ribosomal protein L6]]
*[[Ribosomal protein L16|Ribosomal protein L16]]
*[[Ribosomal protein L17|Ribosomal protein L17]]
*[[Ribosomal protein L18|Ribosomal protein L18]]
*[[Ribosomal protein L19|Ribosomal protein L19]]
*[[Ribosomal protein L2|Ribosomal protein L2]]
*[[Ribosomal protein L20|Ribosomal protein L20]]
*[[Ribosomal protein L21|Ribosomal protein L21]]
*[[Ribosomal protein L22|Ribosomal protein L22]]
*[[Ribosomal protein L23|Ribosomal protein L23]]
*[[Ribosomal protein L24|Ribosomal protein L24]]
*[[Ribosomal protein L25|Ribosomal protein L25]]
*[[Ribosomal protein L27|Ribosomal protein L27]]
*[[Ribosomal protein L29|Ribosomal protein L29]]
*[[Ribosomal protein L3|Ribosomal protein L3]]
*[[Ribosomal protein L30|Ribosomal protein L30]]
*[[Ribosomal protein L31|Ribosomal protein L31]]
*[[Ribosomal protein L32|Ribosomal protein L32]]
*[[Ribosomal protein L33|Ribosomal protein L33]]
*[[Ribosomal protein L34|Ribosomal protein L34]]
*[[Ribosomal protein L35|Ribosomal protein L35]]
*[[Ribosomal protein L36|Ribosomal protein L36]]
*[[Ribosomal protein L4|Ribosomal protein L4]]
*[[Ribosomal protein L5|Ribosomal protein L5]]
*[[Ribosomal protein L6|Ribosomal protein L6]]
*[[Ribosomal protein L9|Ribosomal protein L9]]


==Reference==
==Reference==
<ref group="xtra">PMID:15554968</ref><references group="xtra"/>
<ref group="xtra">PMID:015554968</ref><references group="xtra"/>
[[Category: Deinococcus radiodurans]]
[[Category: Deinococcus radiodurans]]
[[Category: Fucini, P.]]
[[Category: Fucini, P.]]
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[[Category: 50s ribosome]]
[[Category: 50s ribosome]]
[[Category: Pleuromutilin]]
[[Category: Pleuromutilin]]
[[Category: Ribosome]]
[[Category: Tiamulin]]
[[Category: Tiamulin]]

Revision as of 03:58, 26 July 2012

File:1xbp.png

Template:STRUCTURE 1xbp

Inhibition of peptide bond formation by pleuromutilins: The structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with Tiamulin

Template:ABSTRACT PUBMED 15554968

About this Structure

1xbp is a 30 chain structure of Ribosomal protein L11, Ribosomal protein L13, Ribosomal protein L14, Ribosomal protein L15, Ribosomal protein L16, Ribosomal protein L17, Ribosomal protein L18, Ribosomal protein L19, Ribosomal protein L2, Ribosomal protein L20, Ribosomal protein L21, Ribosomal protein L22, Ribosomal protein L23, Ribosomal protein L24, Ribosomal protein L25, Ribosomal protein L27, Ribosomal protein L29, Ribosomal protein L3, Ribosomal protein L30, Ribosomal protein L31, Ribosomal protein L32, Ribosomal protein L33, Ribosomal protein L34, Ribosomal protein L35, Ribosomal protein L36, Ribosomal protein L4, Ribosomal protein L5, Ribosomal protein L6 and Ribosomal protein L9 with sequence from Deinococcus radiodurans. Full crystallographic information is available from OCA.

See Also

Reference

  1. Schlunzen F, Pyetan E, Fucini P, Yonath A, Harms JM. Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin. Mol Microbiol. 2004 Dec;54(5):1287-94. PMID:15554968 doi:10.1111/j.1365-2958.2004.04346.x

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