1dna: Difference between revisions

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Revision as of 05:25, 26 July 2012

File:1dna.png

Template:STRUCTURE 1dna

D221(169)N MUTANT DOES NOT PROMOTE OPENING OF THE COFACTOR IMIDAZOLIDINE RING

Template:ABSTRACT PUBMED 9753479

About this Structure

1dna is a 2 chain structure of Thymidylate synthase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  1. Sage CR, Michelitsch MD, Stout TJ, Biermann D, Nissen R, Finer-Moore J, Stroud RM. D221 in thymidylate synthase controls conformation change, and thereby opening of the imidazolidine. Biochemistry. 1998 Sep 29;37(39):13893-901. PMID:9753479 doi:10.1021/bi9810510

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