2hz0: Difference between revisions

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{{Seed}}
[[Image:2hz0.png|left|200px]]
[[Image:2hz0.png|left|200px]]


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{{STRUCTURE_2hz0|  PDB=2hz0  |  SCENE=  }}  
{{STRUCTURE_2hz0|  PDB=2hz0  |  SCENE=  }}  


===Abl kinase domain in complex with NVP-AEG082===
===Abl kinase domain in complex with NVP-AEG082===


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{{ABSTRACT_PUBMED_17164530}}
{{ABSTRACT_PUBMED_17164530}}


==Disease==
==About this Structure==
Known disease associated with this structure: Leukemia, Philadelphia chromosome-positive, resistant to imatinib OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=189980 189980]]
[[2hz0]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HZ0 OCA].


==About this Structure==
==See Also==
2HZ0 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HZ0 OCA].
*[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:17164530</ref><references group="xtra"/>
<ref group="xtra">PMID:017164530</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
Line 34: Line 22:
[[Category: Liebetanz, J.]]
[[Category: Liebetanz, J.]]
[[Category: Manley, P.]]
[[Category: Manley, P.]]
[[Category: Transferase]]
[[Category: Tyrosine kinase]]
[[Category: Tyrosine kinase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:08:53 2009''

Revision as of 06:26, 26 July 2012

File:2hz0.png

Template:STRUCTURE 2hz0

Abl kinase domain in complex with NVP-AEG082

Template:ABSTRACT PUBMED 17164530

About this Structure

2hz0 is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Cowan-Jacob SW, Fendrich G, Floersheimer A, Furet P, Liebetanz J, Rummel G, Rheinberger P, Centeleghe M, Fabbro D, Manley PW. Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia. Acta Crystallogr D Biol Crystallogr. 2007 Jan;63(Pt 1):80-93. Epub 2006, Dec 13. PMID:17164530 doi:https://dx.doi.org/10.1107/S0907444906047287

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