3elm: Difference between revisions
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[[Image:3elm.png|left|200px]] | |||
[[Image:3elm. | |||
{{STRUCTURE_3elm| PDB=3elm | SCENE= }} | {{STRUCTURE_3elm| PDB=3elm | SCENE= }} | ||
===Crystal Structure of MMP-13 Complexed with Inhibitor 24f=== | ===Crystal Structure of MMP-13 Complexed with Inhibitor 24f=== | ||
{{ABSTRACT_PUBMED_19422229}} | {{ABSTRACT_PUBMED_19422229}} | ||
==About this Structure== | ==About this Structure== | ||
[[3elm]] is a 2 chain structure of [[Matrix metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ELM OCA]. | |||
==See Also== | |||
*[[Matrix metalloproteinase|Matrix metalloproteinase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019422229</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Koehn, J.]] | [[Category: Koehn, J.]] | ||
[[Category: Kulathila, R.]] | [[Category: Kulathila, R.]] | ||
[[Category: Monovich, L.]] | [[Category: Monovich, L.]] | ||
[[Category: Carboxylate inhibitor]] | [[Category: Carboxylate inhibitor]] | ||
[[Category: Collagen degradation]] | [[Category: Collagen degradation]] | ||
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[[Category: Metalloprotease]] | [[Category: Metalloprotease]] | ||
[[Category: Mmp-13]] | [[Category: Mmp-13]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 06:53, 26 July 2012
Crystal Structure of MMP-13 Complexed with Inhibitor 24f
Template:ABSTRACT PUBMED 19422229
About this Structure
3elm is a 2 chain structure of Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Monovich LG, Tommasi RA, Fujimoto RA, Blancuzzi V, Clark K, Cornell WD, Doti R, Doughty J, Fang J, Farley D, Fitt J, Ganu V, Goldberg R, Goldstein R, Lavoie S, Kulathila R, Macchia W, Parker DT, Melton R, O'Byrne E, Pastor G, Pellas T, Quadros E, Reel N, Roland DM, Sakane Y, Singh H, Skiles J, Somers J, Toscano K, Wigg A, Zhou S, Zhu L, Shieh WC, Xue S, McQuire LW. Discovery of potent, selective, and orally active carboxylic acid based inhibitors of matrix metalloproteinase-13. J Med Chem. 2009 Jun 11;52(11):3523-38. PMID:19422229 doi:10.1021/jm801394m
